Results 31 to 40 of about 1,648 (134)

The Concise Guide to PHARMACOLOGY 2025/26: Introduction and Other Protein Targets

British Journal of Pharmacology, Volume 182, Issue S1, Page S1-S23, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, John A. Cidlowski, Anthony P. Davenport, Doriano Fabbro, Michael Spedding, Jörg Striessnig, Jane F. Armstrong, O. Peter Buneman, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Katelin E. Ahlers‐Dannen, Mohammed Alqinyah, Thiruma V. Arumugam, Christopher Bodle, Josephine Buo Dagner, Bandana Chakravarti, Shreoshi P. Choudhuri, Kirk M. Druey, Rory A. Fisher, Kyle J. Gerber, John R. Hepler, Shelley B. Hooks, Havish S. Kantheti, Behirda Karaj, Somayeh Layeghi‐Ghalehsoukhteh, Jae‐Kyung Lee, Zili Luo, Kirill Martemyanov, Luke D. Mascarenhas, Harrison McNabb, Carolina Montañez‐Miranda, Osita Ogujiofor, Hoa Phan, David L. Roman, Vincent Shaw, Benita Sjogren, Christopher Sobey, Mackenzie M. Spicer, Katherine E. Squires, Laurie Sutton, Menbere Wendimu, Thomas Wilkie, Keqiang Xie, Qian Zhang, Yalda Zolghadri   +51 more
wiley   +1 more source

Functional identification and characterization of sodium binding sites in Na symporters [PDF]

, 2013
Sodium cotransporters from several different gene families belong to the leucine transporter (LeuT) structural family. Although the identification of Na(+) in binding sites is beyond the resolution of the structures, two Na(+) binding sites (Na1 and Na2)
Loo, Donald DF, Jiang, Xuan, Wright, Ernest M, Gorraitz, Edurne, Hirayama, Bruce A   +4 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

Relative domain folding and stability of a membrane transport protein [PDF]

, 2014
There is a limited understanding of the folding of multidomain membrane proteins. Lactose permease (LacY) of Escherichia coli is an archetypal member of the major facilitator superfamily of membrane transport proteins, which contain two domains of six ...
Findlay, Heather E., Findlay, Heather E, Harris, Nicola J., Booth, Paula J., Harris, Nicola J, Booth, Paula J, Simms, John, Liu, Xia, Harris, Nicola J; id_orcid   +8 more
core   +1 more source

Elucidating the Mechanism Behind Sodium-Coupled Neurotransmitter Transporters by Reconstitution

, 2022
Sodium-coupled neurotransmitter transporters play a fundamental role in the termination of synaptic neurotransmission, which makes them a major drug target.
Loland, Claus J., Schmidt, Solveig G., Gether, Ulrik   +2 more
core   +1 more source

Deciphering the Sodium Sensing Mechanisms in Glycophytes and Halophytes

Plant, Cell &Environment, Volume 48, Issue 12, Page 8586-8603, December 2025.
ABSTRACT Plants, including halophytes (salt‐tolerant) and glycophytes (salt‐sensitive), have developed diverse molecular mechanisms and morphological adaptations to survive in saline environments. The cellular components and molecular processes for salinity sensing and stress tolerance have been extensively identified in glycophytes, but not so with ...
Rabia Areej Cheema, Hafiz Mamoon Rehman, Sehar Nawaz, Shakeel Ahmad, Hon‐Ming Lam   +4 more
wiley   +1 more source

Differential resistance to cell entry by porcine endogenous retrovirus subgroup A in rodent species [PDF]

, 2007
Background: The risk of zoonotic infection by porcine endogenous retroviruses (PERV) has been highlighted in the context of pig-to-human xenotransplantation. The use of receptors for cell entry often determines the host range of retroviruses.
Matouskova, M, Mattiuzzo Giada, Takeuchi Yasuhiro, Matouskova Magda, Giada Mattiuzzo, Mattiuzzo, G, Takeuchi, Y, Magda Matouskova, Yasuhiro Takeuchi   +8 more
core   +1 more source

Construction of a Fluorescence‐Based Logic Gate Seeing the Effect of Perchlorate Ions on Hemicyanine Dye–β‐Cyclodextrin Complexes to Certify Safe Drinking Water

ChemistryOpen, Volume 14, Issue 10, October 2025.
A method to detect perchlorate ions and certify safe drinking water by constructing a fluorescence‐based logic gate considering the binding of a hemicyanine dye with β‐CD is presented. Perchlorate ions (ClO4−) are prevalent contaminants in the surface, and drinking water that disrupt thyroid function by competitively inhibiting the sodium‐iodide ...
Anusha C. M., Shalini Dyagala, Sairathna Choppella, Mahesh Kumar Ravva, Subit Kumar Saha   +4 more
wiley   +1 more source

Gene Expression Associated With Behaviour Manipulation in Wood Ants Infected With Larval Lancet Fluke, Dicrocoelium dendriticum

Molecular Ecology, Volume 34, Issue 20, October 2025.
ABSTRACT Many ant species show dramatic shifts in behaviour when infected with parasites, but the molecular basis of these behavioural changes is not well understood. An example is the wood ant, Formica aserva, which serves as an intermediate host for the lancet liver fluke, Dicrocoelium dendriticum.
Chen‐Hua Li, Cameron P. Goater, James D. Wasmuth   +2 more
wiley   +1 more source

Prenatal Diagnosis of Bartter Syndrome: Lessons From a Complex Diagnostic Procedure

Clinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT Bartter syndrome is an idiopathic condition that may manifest antenatally, characterized by a spectrum of symptoms including maternal polyhydramnios, prematurity, polyuria, hypercalciuria, nephrocalcinosis, normomagnesemia, vomiting, growth retardation, and elevated renal synthesis and urinary excretion of prostaglandins.
Athina A. Samara, Paschalis Mousios, Paraskevas Perros, Antonios Koutras, Emmanouil Manolakos, Eleftherios Anastasakis, Chara Skentou, Konstantinos Dafopoulos, Antonios Garas, Sotirios Sotiriou   +9 more
wiley   +1 more source