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Effects of sodium arsenite on fetal development

Bulletin of Environmental Contamination and Toxicology, 1972
Single intraperitoneal injections of sodium arsenite were given to albino Swiss-Webster mice on one of days 7–12 of gestation. Two dose levels were used: 10 or 12 mg/kg. Arsenite treatment resulted in high rates of fetal deaths and tended to decrease fetal weights-compared with H2O injected controls. Arsenite induced a variety of fetal malformations on
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Comparative in vitro effects of sodium arsenite and sodium arsenate on neuroblastoma cells

Toxicology, 1994
The toxic effects of arsenic at different cellular levels were assessed using two inorganic chemical species: sodium arsenite and sodium arsenate, representing the trivalent and pentavalent states of arsenic, respectively. Mouse neuroblastoma cell cultures (Neuro-2a) were exposed for 24 h, and cytotoxic effects evaluated were: cell proliferation by ...
G, Repetto, P, Sanz, M, Repetto
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The reaction of sodium arsenite with sodium chlorite

Analytica Chimica Acta, 1952
Abstract Existing procedures for the standardisation of sodium chlorite solutions are critically examined and a suitable method detailed. The reaction between sodium chlorite and sodium arsenite solutions is discussed; reaction is quantitative in the presence of sodium bicarbonate and osmic acid as catalyst.
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Influence of Sodium Arsenite on Microflora of Soil

Botanical Gazette, 1924
1. Sodium arsenite applied to a soil greatly increases the number of organisms in that soil which will develop on synthetic agar. 2. In only three dilute concentrations were the ammonifiers stimulated by the addition of sodium arsenite to a soil. The soil in which stimulation was noted was a calcareous loam high in organic content.
J. E. Greaves, E. G. Carter
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The effects of sodium arsenite exposure on behavioral parameters in the rat

Brain Research Bulletin, 2001
Arsenic is a metalloid widely present in the environment. It is found in well water, soil, and air, and is also released from mining residues and industrial debris, among other anthropogenic sources. It has been previously reported that the content of catecholamines in striatum, hippocampus, and other cerebral regions changes in mice and rats exposed ...
V M, Rodríguez   +4 more
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Acute toxicity of sodium arsenite in a complex food matrix

Food and Chemical Toxicology, 2007
Acute toxicity of a single oral dose of sodium arsenite (As), administered in half and half cream (HH), was assessed in male and non-pregnant female rats (0.41, 4.1, 41.0 and 410.0mg/kg body weight) and pregnant rats (0.41, 4.1 and 41.0mg/kg body weight). Control rats received deionized water alone, HH alone or 41.0mg/kg As in deionized water (41 mg/kg
R L, Sprando   +5 more
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In vitro effect of sodium arsenite on Echinococcus granulosus protoscoleces

Molecular and Biochemical Parasitology, 2016
Cystic echinococcosis (CE) caused by the metacestodes of Echinococcus granulosus is an important cosmopolitan zoonosis. Surgery is the main treatment option for CE. Meanwhile, chemotherapy is used as an significant adjunct to surgery. However, the benzimidazole carbamate group and the existing scolicidal agents may not be as effective as hoped. In this
Guoqiang, Xing   +9 more
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Effects of sodium arsenite exposure on development and behavior in the rat

Neurotoxicology and Teratology, 2002
Arsenic is an environmental contaminant found in soil, water and air in some zones of the world. It has been widely studied for its effects as a human carcinogenic agent, but few studies have dealt with neurobehavioral effects. In addition, studies of arsenic effects on development have only addressed its effects on embryotoxicity and teratogenicity ...
V M, Rodríguez   +4 more
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Oxidative metabolism of lung macrophages exposed to sodium arsenite

Toxicology in Vitro, 2007
Arsenic pollution has become increasingly severe. It occurs as the result of geological processes and different human activities. Arsenic toxicity at the respiratory level occurs mainly by inhalation of products of coal combustion. The aim of this study was to evaluate sodium arsenite (As(3+)) toxicity in murine alveolar macrophages (AMs) in vitro and ...
Mónica A, Palmieri   +2 more
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Inhibition of mitotic-specific histone phosphorylation by sodium arsenite

Toxicology in Vitro, 1995
Synchronized cultures of Chinese hamster cells (line CHO) were used to measure the effects of 10 mum sodium arsenite on histone phosphorylation. This treatment caused cell proliferation to be temporarily arrested, after which the cells spontaneously resumed cell proliferation in a radiomimetic manner.
Cobo, J. M.   +2 more
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