Results 111 to 120 of about 366,375 (330)

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

open access: yesAdvanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova   +5 more
wiley   +1 more source

Synthesis of dawsonites [PDF]

open access: yes, 1982
Alkali metal and ammonium dawsonites can be prepared by a nonaqueous process according to which equimolar quantities of the corresponding hydrogen carbonate and aluminum hydroxide in finely divided state are heated together to a tempeature within the ...
Altman, R. L.
core   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

open access: yesAdvanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer   +10 more
wiley   +1 more source

Compounded medicines: tailored solution for rare diseases – the case of Urea Cycle Disorders and Primary Distal Tubular Acidosis. [PDF]

open access: yesBatna Journal of Medical Sciences
Introduction: Rare diseases are those with a prevalence of 1 in 2,000. These include urea cycle disorders (UCDs) and primary distal tubular metabolic acidosis (DTA).
Chahinez NEHAL   +7 more
doaj   +1 more source

Mitochondrial proteomics: analysis of a whole mitochondrial extract with two-dimensional electrophoresis [PDF]

open access: yes, 2008
Mitochondria are complex organelles, and their proteomics analysis requires a combination of techniques. The emphasis in this chapter is made first on mitochondria preparation from cultured mammalian cells, then on the separation of the mitochondrial ...
A. Gorg   +16 more
core   +6 more sources

The Space Within: How Architected Voids Promote Tissue Formation

open access: yesAdvanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou   +3 more
wiley   +1 more source

Optimising acid-base balance in patients with advanced chronic kidney disease: a quality improvement initiative

open access: yesBMJ Open Quality
Advanced chronic kidney disease (CKD) is commonly associated with disturbances in acid-base balance. Studies have shown that correcting metabolic acidosis in CKD offers several clinical benefits, including slower disease progression and reduced mortality.
Jyoti Baharani, Laura Desai
doaj   +1 more source

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