Results 181 to 190 of about 212,598 (239)

Combination of Lenvatinib and Antibiotics: A Potential Approach to Enhance Sensitivity in Differentiated Thyroid Cancer

International Journal of Cancer, EarlyView.
Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger, Petra Huber‐Cantonati, Daniela D. Weber, Sarah Pichler, Georg Schischkow, Marta Garcia‐Miralles, Christian Pirich, Gundula Rendl, Teresa Kiener, Thomas Felder, Martin Geroldinger, Robert Terkola, Barbara Kofler, Johanna Pachmayr   +13 more
wiley   +1 more source

Sodium bicarbonate use in the treatment of idiopathic intracranial hypertension. [PDF]

Eye (Lond)
Baker MJ, Jiang Z, McClelland C, Lee MS.
europepmc   +1 more source

Unraveling the Plasma Extracellular Vesicles Proteome: Predictors of Resistance in Immunotherapy of Advanced Melanoma

International Journal of Cancer, EarlyView.
ABSTRACT Despite substantial clinical benefit from immune checkpoint inhibitors (ICI), advanced melanoma remains challenging due to frequent treatment resistance. Resistance may be intrinsic (primary) or emerge over time (secondary). Biomarkers predicting distinct resistance phenotypes before therapy are lacking.
Julian Kött, Glenn Geidel, Carmen M. T. Roeper, Lucija Ačkar, Bente Siebels, Hannah Voß, Hartmut Schlüter, Michaela Schweizer, Kilian Müller, Alessandra Rünger, Tim Zell, Benjamin Deitert, Ali Zeinal‐Abedini, Isabel Heidrich, Stefan W. Schneider, Klaus Pantel, Daniel J. Smit, Christoffer Gebhardt   +17 more
wiley   +1 more source

Development and Characterization of Sodium Bicarbonate-Based Gel for Cytolytic Vaginosis. [PDF]

Pharmaceutics
Gaspar C, Agonia AS, Felício S, Tomás M, Esteves D, Palmeira-de-Oliveira R, Donders GGG, Martinez-de-Oliveira J, Palmeira-de-Oliveira A.   +8 more
europepmc   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

Exploring the effects of outdoor physical work in the heat, with or without sodium bicarbonate supplementation, on markers of acute kidney injury. [PDF]

Physiol Rep
Siegler J, Butterick B, Freire R, Specht J, Amorim F.   +4 more
europepmc   +1 more source

Hepatic Encephalopathy and Age Were Assessed to Ameliorate the Underestimation of the Model for End‐Stage Liver Disease Score in Patients With Acute‐on‐Chronic Liver Failure

iNew Medicine, EarlyView.
This study demonstrates that the model for end‐stage liver disease (MELD) score significantly underestimates 90‐day mortality in acute‐on‐chronic liver failure (ACLF) patients (AUC: 0.556) compared to non‐ACLF patients (area under the receiver operating characteristic curve [AUC]: 0.848).
Guanghou Chen, Qifei Guan, Yufeng Gao, Zhenhua Zhang, Hongchuan Zhao, Beicheng Sun   +5 more
wiley   +1 more source

Effects of sodium bicarbonate therapy on cognitive and cerebrovascular function in midlife and older adults with chronic kidney disease: a pilot randomized trial. [PDF]

BMC Nephrol
Gu F, You Z, Hawkins N, Reddin R, Hamour R, Shapiro A, Coughlan C, Seals D, Furgeson S, Dixon A, Nowak KL, Kendrick J.   +11 more
europepmc   +1 more source

CO2 capture by accelerated weathering of limestone using waste limestone at elevated CO2 concentrations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Accelerated weathering of limestone (AWL) using waste limestone (WL) for industrially relevant CO2 capture remains underexplored. Previous studies on potable water‐operated AWL have mainly examined idealised conditions, such as the use of high‐purity limestone or relatively low CO2 concentrations, which may not reflect selected ...
Daniel Nyuin Alfred Damu, Alvin Guo Jian Lee, Slyvester Yew Wang Chai, Lock Hei Ngu   +3 more
wiley   +1 more source

Acute Co-Ingestion of Caffeine and Sodium Bicarbonate on Muscular Endurance Performance. [PDF]

Nutrients
Montalvo-Alonso JJ, Munilla C, Garriga-Alonso L, Ferragut C, Valadés D, Gonzalo-Encabo P, Pérez-López A.   +6 more
europepmc   +1 more source