Results 81 to 90 of about 1,511,406 (316)

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He   +9 more
wiley   +1 more source

Sodium bicarbonate treatment for QRS widening in bupropion overdoses [PDF]

open access: yes, 2023
Bupropion cardiotoxicity widens QRS complexes by inhibiting cardiac gap junctions. Sodium bicarbonate is the standard treatment for QRS widening from sodium channel blockade, but its effect on QRS widening in bupropion cardiotoxicity is not well-studied.
Linda Johnson (1555708)   +2 more
core   +1 more source

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco   +7 more
wiley   +1 more source

Efficacy and safety of oral sodium bicarbonate in kidney-transplant recipients and non-transplant patients with chronic kidney disease: a systematic review and meta-analysis

open access: yesFrontiers in Pharmacology
IntroductionWe investigated the efficacy and safety of oral sodium bicarbonate in kidney-transplant recipients and non-transplant patients with chronic kidney disease (CKD), which are currently unclear.MethodsPubMed, Cochrane Library, Embase, and Web of ...
Yun Wu   +10 more
doaj   +1 more source

Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine

open access: yesNew England Journal of Medicine, 2017
Background Intravenous sodium bicarbonate and oral acetylcysteine are widely used to prevent acute kidney injury and associated adverse outcomes after angiography without definitive evidence of their efficacy.
S. Weisbord   +18 more
semanticscholar   +1 more source

Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman   +7 more
wiley   +1 more source

Current Evidence on the Adverse Effects of Sodium Bicarbonate used in Bread Processing on Human Health: A Systematic Review

open access: yesمجله اپیدمیولوژی ایران, 2013
Background & Objectives: In the last decade, there have been some claims about hazards of Sodium bicarbonate in bread, in public and scientific sites. Currently, the use of sodium bicarbonate in bread processing is forbidden in Iran.
E Pourbakhtyaran   +5 more
doaj  

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

open access: yesAdvanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno   +15 more
wiley   +1 more source

Eco-friendly Flame-Retardant Cellulose Nanofibril Aerogels by Incorporating Sodium Bicarbonate

open access: yesACS Applied Materials and Interfaces, 2018
Cellulose nanofiber (CNF) aerogels offer excellent thermal insulation properties, but high flammability restricts their application. In this study, CNF aerogels were prepared by incorporating sodium bicarbonate (SBC), which effectively improved the fire ...
M. Farooq   +3 more
semanticscholar   +1 more source

Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? : Study protocol for a randomized controlled trial [PDF]

open access: yes, 2015
Date of acceptance: 01/07/2015 © 2015 Witham et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
McMurdo, Marion E. T.   +23 more
core   +1 more source

Home - About - Disclaimer - Privacy