Results 51 to 60 of about 512,458 (303)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effectiveness of Sodium bisulfate and Calcium carbonate litter amendments on the Microbial load of Broiler Built-up Litter

SVU-International Journal of Veterinary Sciences, 2021
In the poultry industry, litter treatment is an effective tool used to control microbial growth, public health risk, and the environmental impact of built-up litter.
Elshaimaa Ismael, Eman Mohamed Ismail
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Biomass-derived carbon materials for energy storage applications [PDF]

, 2021
Energy storage systems are an essential link in the implementation of renewable energies and in the development of electric vehicles, which are needed to reduce our dependence on fossil fuels and the emission of greenhouse gases.
Gómez Martín, Aurora
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

The effects of dietary cation-anion difference and dietary buffer for lactating dairy cattle under mild heat stress with night cooling

Journal of Dairy Science
: The objective of this study was to investigate the interactive effect of DCAD and dietary buffer supply on DMI, ruminal fermentation, milk and milk component yields, and gastrointestinal tract (GIT) permeability in lactating dairy cattle exposed to ...
C.A. Bertens, C. Stoffel, M.B. Crombie, P. Vahmani, G.B. Penner   +4 more
doaj   +1 more source

Experiments on the production of a highly dispersible calcium carbonate. ('Experimental section' only) [Translation from: Szklo i Ceramiki 30, 133-136, 1979] [PDF]

, 1986
This short translation summarises experiments on the production of a highly dispersible precipitate of calcium carbonate.
Domka, L.
core  

One-electron oxidation and reduction of glycosaminoglycan chloramides: a kinetic study. [PDF]

, 2013
Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, these being significant components of the extracellular matrix (ECM).
A.W.J. Paterson, Akeel, Al-Assaf, Al-Assaf, B.J. Parsons, Balazs, C. Houee-Levin, Camenisch, Chawla, D.J. Heyes, Dogliotti, Eriksen, Hardingham, Hawkins, Hayon, Hayon, Heckel, Heinecke, Huie, Ivanov, J.-L. Marignier, Jiang, Johnson, Kennett, Kennett, Kettle, Laurent, Laurent, McElroy, McElroy, McGowan, Milner, Misra, Parsons, Parsons, Pattison, Pattison, Pattison, Pe Myint, Poskrebyshev, Redpath, Rees, Rees, Rees, Rees, Rees, Rees, S. Sibanda, Schwarz, Stern, Swallow, Tang, Thomas, Thomas, Thorne, Toole, Toole, Toole, Turley, van Golen, von Sonntag, Weeks, Weiss, Weiss, Wine, Wolfenden, Woods, Zao   +67 more
core   +1 more source