Results 131 to 140 of about 49,773 (253)

Distinct impacts of sodium channel blockers on the strength-duration properties of human motor cortex neurons. [PDF]

Epilepsia
Rocchi L, Brown K, Di Santo A, Smith H, Peterchev AV, Rothwell JC, Hannah R.   +6 more
europepmc   +1 more source

PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers. [PDF]

J Am Coll Cardiol, 2016
Syeda F, Holmes AP, Yu TY, Tull S, Kuhlmann SM, Pavlovic D, Betney D, Riley G, Kucera JP, Jousset F, de Groot JR, Rohr S, Brown NA, Fabritz L, Kirchhof P.   +14 more
europepmc   +1 more source

Ultrathin Li Metal Anodes: Quantitative Design Principles and Manufacturability Across Liquid and Solid‐State Batteries

Advanced Materials, EarlyView.
Ultrathin lithium metal anodes (≤15 µm) offer a promising route to high‐energy‐density batteries due to their high capacity and low potential. This review presents design principles for ultrathin Li, evaluates fabrication strategies, and discusses challenges in liquid and solid‐state cells.
Cheng Wang, Caoyu Wang, Shuixin Xia, Jodie A. Yuwono, Mingnan Li, Yanqiu Lyu, Ruizhi Zhang, Jun Wang, Jianfeng Mao, Zaiping Guo   +9 more
wiley   +1 more source

Precision Medicine: SCN8A Encephalopathy Treated with Sodium Channel Blockers. [PDF]

Neurotherapeutics, 2016
Møller RS, Johannesen KM.
europepmc   +1 more source

Second‐Harmonic Hyper‐Mie Optical Activity Enables Closed‐Loop Chiral Photochemistry

Advanced Materials, EarlyView.
Nonlinear chiral photochemistry is demonstrated in CdTe/CdO nanohelices, where circularly polarized infrared light both drives and tracks photo‐oxidation via second‐harmonic scattering. This closed‐loop process reveals real‐time structural evolution, including shell fracturing and core exposure, accompanied by a transition from hyper‐Mie to hyper ...
Hoyeon Choi, Kody Whisnant, Ben J. Olohan, E. Petronijevic, G. Dan Pantoș, Nicholas A. Kotov, Ventsislav K. Valev   +6 more
wiley   +1 more source

Novel Sulfonamide Derivatives as Nav1.5 Sodium Channel Blockers for Treating Atrial Fibrillation. [PDF]

ACS Med Chem Lett
Feng S, Liang SH.
europepmc   +1 more source

Discovery and evaluation of nNa_v1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells. [PDF]

Bioorg Med Chem, 2018
Dutta S, Lopez Charcas O, Tanner S, Gradek F, Driffort V, Roger S, Selander K, Velu SE, Brouillette W.   +8 more
europepmc   +1 more source

Linker‐Engineered Dimeric Acceptors Afford Efficient Organic Photocatalytic Hydrogen Evolution via Tailored Nanomorphology for Long‐Lived Charge Accumulation

Advanced Materials, EarlyView.
We developed a new series of monomeric (MY) and dimeric acceptors incorporating unfused (DY1) and fused (DY2) linkers, which establish a controlled self‐aggregation trend of MY > DY2 > DY1. The DY2‐based system yields a bulk‐heterojunction nanoparticle morphology that appears to balance phase separation and interfacial accessibility, consistent with ...
Jin‐Woo Lee, Cheng Sun, Yang Song, Guanru Dong, Keren Ai, Stanley Alfred Cazaly, Flurin Eisner, Bumjoon J. Kim, Zeinab Hamid, Iain McCulloch, Yun‐Hi Kim, James R. Durrant   +11 more
wiley   +1 more source

E. coli Extracellular Matrix: A Tunable Composite With Hierarchical Structure

Advanced Materials, EarlyView.
The complex composite‐like mechanical behavior of E. coli biofilm matrix is the result of a synergic contribution of the rigid curli and swelling pEtN‐cellulose, and emerges from specific ratio and assembly conditions. The interactions between the two fibers govern biofilm hydration and characteristic wrinkling patterns, providing crucial insights for ...
Macarena Siri, Agustín Mangiarotti, Anne Seewald, Nikolai Rosenthal, Shahrouz Amini, Emeline Raguin, Peter Fratzl, Cécile M. Bidan   +7 more
wiley   +1 more source

Design, Synthesis, and Evaluation of Sodium Channel Blockers with Anti-invasive Activities in Medullary Thyroid Cancer. [PDF]

ACS Med Chem Lett
Pukkanasut P, Dutta S, Whitt J, Babu P, Lopez-Charcas O, Anguheven-Ledezma TG, Gomora JC, Jaskula-Sztul R, Velu SE.   +8 more
europepmc   +1 more source