Results 81 to 90 of about 1,549,517 (369)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Contrast-induced acute kidney injury and renal support for acute kidney injury : a KDIGO summary (part 2) [PDF]

open access: yes, 2013
Acute kidney injury (AKI) is a common and serious problem affecting millions and causing death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes completed the first ever international multidisciplinary clinical practice ...
Kellum, John A, Lameire, Norbert
core   +2 more sources

Stabilization of Penicillin-Salt Solutions with Sodium Citrate [PDF]

open access: yesNature, 1947
Abstract Sodium citrate has a considerable stabilising effect on penicillin salts solutions even in higher concentrations. The optimal molar concentration of sodium citrate varies with the concentration of the penicillin salt solutions and appears to be conditioned by the amount of buffers included in the impurities of the various samples ...
openaire   +4 more sources

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Efficacy of buffered sodium citrate alone and in combination with sodium diacetate againstListeria monocytogenes on beef franks [PDF]

open access: yes, 2003
We assessed the antimicrobial efficacy of buffered sodium citrate alone and in combination with sodium diacetate against L. monoyctogenes on beef frank samples stored at 39°F. Initial inoculum level of L.
Ceylan, E.   +2 more
core   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Sodium potassium hydrogen citrate, NaKHC6H5O7

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
The crystal structure of sodium potassium hydrogen citrate has been solved and refined using laboratory X-ray powder diffraction data, and optimized using density functional theory techniques.
Alagappa Rammohan, James A. Kaduk
doaj   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Sodium citrate inhibits the proliferation of human gastric adenocarcinoma epithelia cells.

open access: yesOncology Letters, 2018
The objective of the present study was to investigate the cytotoxic effects of sodium citrate on human gastric adenocarcinoma epithelia AGS cells. Numerous cytotoxicity-associated sodium citrate-induced effects were assessed, including cell viability and
Yuan Xia   +4 more
semanticscholar   +1 more source

Efficacy of oral citrate administration in primary hyperoxaluria [PDF]

open access: yes, 2017
Urinary citrate is a potent inhibitor of calcium oxalate (CaOx) crystallization, but oral citrate has rarely been used in patients with primary hyperoxaluria (PH).
Blau, N.   +3 more
core  

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