Results 61 to 70 of about 2,844,271 (293)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Sodium nitrite-catalyzed oxybromination of aromatic compounds and aryl ketones with a combination of hydrobromic acid and molecular oxygen under mild conditions

open access: yes, 2006
A novel and efficient catalytic system for the oxybromination of aromatic compounds and aryl ketones utilizing a combination of aqueous hydrobromic acid and molecular oxygen in the presence of sodium nitrite under mild conditions has been developed.
Liu, Renhua   +5 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

ELECTROCHEMICAL REDUCTION OF 2,2,5,5-TETRAMETHYLPYRROLINE DERIVATIVES TO CORRESPONDING PYRROLIDINES

open access: yesAdvanced Engineering Research, 2012
The reduction technique of 2,2,5,5-tetramethylpyrroline compounds to pyrrolidines on sodium amalgam preformed under the electrolysis of sodium hydroxide solution is described.
Irina Y. Zhukova   +2 more
doaj  

Producing Kombucha Beads by Spherification: Effect of Alginate Concentration and Exposure-Time on Release Behaviour of Polyphenolic Compounds

open access: yesAgrointek
Encapsulated kombucha was an alternative kombucha product to be added to food product conveniently. This study was investigated the effect of sodium alginate concentration and exposure time on the release of bioactive compounds namely total phenolic ...
Dewi Cakrawati   +3 more
doaj   +1 more source

Synthesis and Characterization of Substituted 4-Methoxy-1H-quinolin-2-ones

open access: yesE-Journal of Chemistry, 2010
An efficient method for the synthesis of various substituted 4-methoxy-1H-quinolin-2-ones from various substituted aniline with malonic acid, phosphorous oxychloride, sodium methoxide and glacial acetic acid under different conditions is described.
A. K. Ramasamy   +2 more
doaj   +1 more source

Solid-State Conversion of Scandium Phosphate into Scandium Oxide with Sodium Compounds

open access: yes, 2019
The application of scandium (Sc) is hindered by insufficient supply. The majority of the world Sc supply is sourced from industrial byproducts, where Sc needs to be separated from other components.
Risto T. Koivula (7054553)   +4 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

ELECTROCHEMICAL REDUCTION OF 2,2,5,5-TETRAMETHYLPYRROLINE DERIVATIVES TO CORRESPONDING PYRROLIDINES

open access: yesВестник Донского государственного технического университета, 2018
The reduction technique of 2,2,5,5-tetramethylpyrroline compounds to pyrrolidines on sodium amalgam preformed under the electrolysis of sodium hydroxide solution is described.
Irina Y. Zhukova   +2 more
doaj  

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