Results 151 to 160 of about 253,651 (355)
Ameliorative Effect of Graviola (Annona muricata) on Mono Sodium Glutamate-Induced Hepatic Injury in Rats: Antioxidant, Apoptotic, Anti-inflammatory, Lipogenesis Markers, and Histopathological Studies. [PDF]
Shukry M +7 more
europepmc +1 more source
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan +9 more
wiley +1 more source
Glutamate transport driven by an electrochemical gradient of sodium ions in Escherichia coli [PDF]
Tomofusa Tsuchiya +2 more
openalex +1 more source
Dietary-Free Glutamate: Implications for Research on Fear-Overconsolidation and PTSD [PDF]
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Bracha, Dr. Stefan +1 more
core
Evaluation of Sodium Poly- , L-glutamate as a Plasma Expander.
Summary(1) A synthetic polypeptide, sodium poly-α, L-glutamate (SPG), has been evaluated as a plasma expander by comparing it with dextran in both normovolemic and hypovolemic dogs. (2) SPG at a concentration of 3% was equivalent to 6% dextran as a plasma expander. (3) Further studies with SPG proved it to be too toxic for clinical trial.
openaire +3 more sources
Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi +18 more
wiley +1 more source
In-vitroClot Forming Properties of Polyelectrolyte Complexes of [2-(Diethylamino)ethyl]dextran Hydrochloride with Poly(sodium-L-glutamate) and of Sodium Carboxymethyldextran with Chitosan [PDF]
Yasuo Kikuchi, Tsutomu Takebayashi
openalex +1 more source
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu +9 more
wiley +1 more source
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang +19 more
wiley +1 more source

