Results 221 to 230 of about 954,955 (289)

Glycosylated dendrimer nanoamplifiers hijack DNA damage‐immune crosstalk for enhanced dual‐track therapy of orthotopic glioblastoma

open access: yesBMEMat, EarlyView.
A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song   +10 more
wiley   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

open access: yesBMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue   +8 more
wiley   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

open access: yesBMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang   +8 more
wiley   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

open access: yesBMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue   +4 more
wiley   +1 more source

Optimizing Instant Rice Quality of Milled and Brown Rice Through Cultivar‐Selection

open access: yesCereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Instant rice products are increasingly favored for convenience; however, achieving consistent quality, particularly rehydration performance and texture, remains a challenge. Rice cultivars differ in physicochemical properties that influence processing behavior and final product quality, yet systematic screening ...
Faith Ouma   +2 more
wiley   +1 more source

Engineering Halide Perovskites With Chalcogen‐Based Compounds: Insights Into Stability, Interfaces, and Device Integration

open access: yesCarbon Energy, EarlyView.
Chalcogen‐based compounds are explored as versatile tools to enhance the stability and performance of halide perovskites. Their roles in defect passivation, ion migration suppression, and interface engineering are analyzed, along with impacts on device efficiency.
Atanu Jana   +4 more
wiley   +1 more source

Synthesis and Reduction of Super‐Bulky Bis(anilido)acridanide Aluminium Complexes

open access: yesChemistry – A European Journal, EarlyView.
A new generation of super‐bulky bis(anilido)acridanide ligands has been developed and used in the preparation of aluminium(III) complexes. ABSTRACT Super‐bulky bis(anilido)acridanide pro‐ligands (NNNAr)H3 (NNNAr = 4,5‐bis(anilido)‐2,7,9,9‐tetramethylacridanide, anilido = NAr, Ar = DCHP, 2,6‐dicyclohexylphenyl; TCHP, 2,4,6‐tricyclohexylphenyl) have been
Matthew J. Evans   +2 more
wiley   +1 more source

Total Synthesis and Absolute Configuration of the Irregular Tetraterpene Viaticene A

open access: yesChemistry – A European Journal, EarlyView.
Viaticenes are tetraterpenes with a unique [6+2]‐connectivity from the springtail Hypogastrura viatica. Here, we report a modular 13‐step total synthesis of viaticene A, featuring stereoselective double‐bond formation, a Cu‐mediated allylic substitution, and Ni/Co‐cocatalyzed vinyl‐alkyl cross‐electrophile coupling as key steps.
Patrick Stamm   +3 more
wiley   +1 more source

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