Results 201 to 210 of about 134,883 (256)

A nonradioactive iodide uptake assay for sodium iodide symporter function

Analytical Biochemistry, 2010
The standard assay for sodium iodide symporter (NIS) function is based on the measurement of radioiodide uptake ((125)I) in NIS-expressing cells. However, cost and safety issues have limited the method from being used widely. Here we describe a simple spectrophotometric assay for the determination of iodide accumulation in rat thyroid-derived cells ...
Yves Ambroise
exaly   +3 more sources

The Sodium-Iodide Symporter

Current Drug Targets - Immune, Endocrine & Metabolic Disorders, 2004
The sodium-iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates active transport of iodide in the thyroid gland and several other extra-thyroidal tissues. This activity has been utilized for many years for imaging the thyroid gland and for treatment of thyroid disease both benign and malignant.
C H, Baker, J C, Morris
openaire   +2 more sources

EXCHANGE REACTIONS OF ALICYCLIC IODIDES WITH SODIUM IODIDE

Canadian Journal of Chemistry, 1951
The activation energies for the exchange reactions between sodium iodide and cyclopentyl, cycloheptyl, cycloöctyl, cyclopentadecyl, and 2-heptyl iodides were all in the range 21 ± 1 kcal. per mole. For cyclohexyl iodide the value was 25.6 kcal. per mole.
S F, VAN STRATEN, R V V, NICHOLLS, C A, WINKLER   +2 more
openaire   +2 more sources

Radiolytic breakdown of sodium iodide (131I) in sodium iodide (131I) capsules

Nuclear Medicine Communications, 1986
Sodium iodide (131I) capsules are widely used for both diagnosis and therapy. The radiochemical purity of both diagnostic and therapeutic capsules in use in Australia was studied by gel chromatography, high voltage electrophoresis and paper chromatography.
J, Bonnyman, B, Van Every
openaire   +2 more sources

Charge transfer in sodium iodide collisions

The Journal of Chemical Physics, 2023
Sodium iodide (NaI) has, over the years, served as a prototype system in studies of non-adiabatic dynamics. Here, the charge transfer collision reactions Na+ + I− ⇆ Na + I (mutual neutralization and ion-pair formation) are studied using an ab initio approach and the total and differential cross sections are calculated for the reactions.
Patrik Hedvall, Michael Odelius, Åsa Larson   +2 more
openaire   +2 more sources

Cloning of the Mouse Sodium Iodide Symporter

Thyroid, 2001
The iodide-concentrating ability of the thyroid gland is essential to the production of thyroid hormone. We report the nucleotide and amino acid sequence of the mouse sodium iodide symporter (mNIS), which mediates this activity within the thyroid gland.
L A, Pinke, D S, Dean, E R, Bergert, C, Spitzweg, C M, Dutton, J C, Morris   +5 more
openaire   +2 more sources

Sodium Iodide Symporter in Health and Disease

Thyroid, 2001
Radioiodine-concentrating activity in thyroid tissues has allowed the use of radioiodine as a diagnostic and therapeutic agent for patients with thyroid disorders such as well-differentiated thyroid cancer. However, some extrathyroidal tissues also take up radioiodine, contributing to unwanted side effects of radioiodine therapy.
D H, Shen, R T, Kloos, E L, Mazzaferri, S M, Jhian   +3 more
openaire   +2 more sources

Sodium/iodide symporter in thyroid cancer

Experimental and Clinical Endocrinology & Diabetes, 2001
[No abstract available]
C. Mian, L. Lacroix, J. M. Bidart, B. Caillou, FILETTI, SEBASTIANO, M. Schlumberger   +5 more
openaire   +4 more sources

Vapor-phase composition above the cadmium iodide-sodium iodide and the thorium tetraiodide-sodium iodide systems

The Journal of Physical Chemistry, 1986
The activities of CdI/sub 2/ in NaI and of ThI/sub 4/ in NaI have been determined by using vapor-phase UV absorption spectroscopy. The activity coefficient, ..gamma.., for the CdI/sub 2/-NaI system was found to be constant below 0.05 mole fraction of CdI/sub 2/ and equal to 0.23. For the ThI/sub 4/-NaI system, ..gamma.. was found to be constant below 0.
openaire   +1 more source