Results 71 to 80 of about 782,872 (231)

Mechanism for the Reduced Dissolution of Ritonavir Tablets by Sodium Lauryl Sulfate [PDF]

Journal of Pharmaceutical Sciences, 2019
Sodium lauryl sulfate (SLS) is an anionic surfactant widely used in pharmaceutical research as a dissolution enhancer for poorly soluble drugs. When SLS was used in ritonavir (RTV) tablet formulation to improve wetting, dissolution of RTV was surprisingly deteriorated in acidic media. To understand this unexpected phenomenon, a systematic investigation,
Yiwang, Guo, Chenguang, Wang, Jiangnan, Dun, Liying, Du, Michael, Hawley, Changquan Calvin, Sun   +5 more
openaire   +2 more sources

Influence of sodium lauryl sulfate micelles on the oxidation of malonic acid by chromic acid [PDF]

, 1992
710-713Malonic acid oxidation by Cr(VI) in the presence of sodium lauryl sulfate micelle is first order each in [Cr(VI)]and [H+] but second order in malonic acid. The oxidation is inhibited by NaLS.
Mishra, S K, Panigrahi, G P
core  

Tablet Dissolution Deterioration by Sodium Lauryl Sulfate - Mechanism and Mitigation Strategies [PDF]

, 2021
University of Minnesota Ph.D. dissertation. July 2021. Major: Pharmaceutics. Advisor: Changquan Sun. 1 computer file (PDF); xii, 137 pages + 2 supplementary files.Dissolution in gastrointestinal tract (GI tract) is critical for oral solid dosage forms ...
Guo, Yiwang
core  

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Stratum Corneum Biomarkers for Differentiating Irritant and Allergic Contact Dermatitis

Contact Dermatitis, EarlyView.
From 126 patients with irritant or allergic contact dermatitis of the hands, stratum corneum tape strips from patch test sites and lesional hand skin were collected and analysed for barrier and immune biomarkers, and machine learning models were trained to separate ICD from ACD.
F. L. de Boer, S. Kezic, Ivone Jakasa, Nique M. Grob, Nariman K. A. Metwally, Jϋrgen Claesen, Karen Ghauharali‐van der Vlugt, Femke S. Beers‐Stet, Wouter Ouwerkerk, Thomas Rustemeyer, Henk F. van der Molen   +10 more
wiley   +1 more source

Colorimetric quantitation of trace amounts of sodium lauryl sulfate in the presence of nucleic acids and proteins

, 1992
A fast and sensitive procedure for the colorimetric detection of sodium lauryl sulfate (SDS) is presented. The assay is based upon the formation of a chloroform-extractable ion pair between lauryl sulfate and methylene blue that is quantified ...
Oesch, F, Arand, Michael; https://orcid.org/, Friedberg, T   +2 more
core   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

Impact of ultraviolet radiation‐induced damage to hair fiber integrity: A multi‐technique physicochemical characterization of surface and cortex properties

International Journal of Cosmetic Science, EarlyView.
UV exposure induces cuticular and cortical damage in natural hair, with oxidative effects and protein degradation comparable to bleaching. However, double bleaching leads to significantly greater structural degradation, emphasizing distinct mechanisms and severity of chemical versus UV‐induced damage. Abstract The combination of chemist techniques is a
Nathana Cindy Barros Silva Ramos, Alzira Xavier Pinto Dini, Viviane Cristina Albarici, Mayara Miranda Ferreira, Caroline Vieira Hercolino, Adriano da Silva Pinheiro, André Rolim Baby, Maria Valéria Robles Velasco   +7 more
wiley   +1 more source

Clinical improvement and scalp microbiome restructuring following a 28‐day piroctone olamine shampoo intervention

International Journal of Cosmetic Science, EarlyView.
A 28‐day clinical study in 41 individuals with oily dandruff showed that a piroctone olamine shampoo improved clinical symptoms while selectively reshaping the scalp bacterial and fungal microbiome toward a less dysbiotic profile. Abstract Objective To evaluate the clinical efficacy of a piroctone olamine–containing shampoo in individuals with oily ...
Spyridon Markos, Lina Praefke, Yiannis Kapetanstatakis, Michail Tsanakas, Evangelos Beletsiotis   +4 more
wiley   +1 more source

The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley   +1 more source