Genes ingenuity pathway analysis unveils smoothelin‐like 1 (SMTNL1) as a key regulatory protein involved in sodium pentobarbital‐induced growth inhibition in breast cancer [PDF]
Pharmacology Research & Perspectives, 2023 We previously reported that sodium pentobarbital inhibited the growth of the breast cancer associated with the normalization of microcirculatory hemodynamics and oxygenation.
Bingwei Li +4 more
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Intraperitoneal injection of sodium pentobarbital has the potential to elicit pain in adult rats (Rattus norvegicus). [PDF]
PLoS ONE, 2020 An effective and pain-free killing method is required to achieve the goal of euthanasia, a "good death". Overdose of sodium pentobarbital (PB) by intraperitoneal (IP) injection is a widely accepted technique in laboratory rats, but questions remain ...
J N Reimer +4 more
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Effects of different anesthetic drugs on electroretinography in mice [PDF]
Scientific ReportsElectrophysiology (ERG) is widely used for retinal function assessment, but the effects of different anesthetics on ERG recordings, particularly in degenerated retinas, remain unclear.
Chaofeng Yu +5 more
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Stability of Sodium Pentobarbital 5w/v% Aqueous Solution During Short‐Term Chilled and Ambient‐Temperature Storage [PDF]
Veterinary Medicine and ScienceThe COVID‐19 pandemic made it difficult to obtain pharmaceutical‐grade injectable anaesthetics used in animal experiments in Japan. To address this problem, it is worth the effort to evaluate whether the use of non‐pharmaceutical‐grade sodium ...
Masakazu Dohi +4 more
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The effect of different immobilization approaches on red-eared sliders [PDF]
Scientific ReportsThe ethical issues surrounding sacrifice methods in animal experimentation have garnered increasing attention, making immobilization and sedation an integral part of the sacrifice process for experimental animals.
Xin Niu +7 more
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Effect of Intravenous Sodium Pentobarbital on Pain and Sensory Abnormalities in Patients with Chronic Non-Cancer Pain: Narrative Literature Review, Research Study, and Illustrative Case Reports [PDF]
Pain and TherapyIntroduction Sodium pentobarbital (SP), a short- to intermediate-acting barbiturate, has limited information in the existing literature. The objectives of this study are to describe (a) the effect of intravenous (IV) SP infusion on pain and sensory ...
Shehnaz Fatima Lakha, Angela Mailis
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Lessons and Recommendations from a Pentobarbital Shortage: US and Canada 2021
Animals, 2022 In 2021, a shortage in the supply of the euthanasia drug pentobarbital sodium affected animal care professionals around the world, including in the United States and Canada.
Kathleen Cooney, Lianna Titcombe
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Data in Brief, 2021 Pentobarbital is used as an alternative in pediatric sedative imaging procedures. Pentobarbital is only available as pharmaceutical powder. Regardless of its clinical use, its manipulation is necessary byhospital pharmacists that must prepare adapted ...
Benjamin Querin +3 more
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Shipin gongye ke-ji, 2023 In this paper, through the direct sleep experiment, the experiment of prolonging the sleep time of pentobarbital sodium, the hypnosis experiment of subthreshold dose of pentobarbital sodium and the sleep latency experiment of pentobarbital sodium, the ...
Yujing YAO +4 more
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Pharmaceutics, 2023 Pentobarbital is a drug of choice to limit motion in children during paediatric procedural sedations (PPSs). However, despite the rectal route being preferred for infants and children, no pentobarbital suppositories are marketed, and therefore they must ...
Matthieu Lebrat +10 more
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