Results 41 to 50 of about 101,959 (260)

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

Advanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni, Kuoran Xing, Bihan Zhang, Baoteng Wang, Yinglu Chen, Jianping Xie, Xiao Sun, Jinping Wang, David Tai Leong   +8 more
wiley   +1 more source

Leptocarpus disjunctus prolongs sleeping time and increases nonrapid eye movement sleep with additional anxiolytic capacity

Journal of Advanced Pharmaceutical Technology & Research, 2017
Leptocarpus disjunctus Mast. (Restionaceae) is an edible plant which has indigenous warnings regarding its side effects which can manifest as dizziness. This study investigated hypnotic and anxiolytic properties using several animal models.
Watchara Damjuti, Thanes Fuangfoo, Chanida Palanuvej, Tingli Li, Nijsiri Ruangrungsi   +4 more
doaj   +1 more source

Bioactive Conductive Ti3C2Tx‐Ce Hydrogel Facilitates Spinal Cord Injury Repair Through ROS Scavenging and Mitochondrial Regulation

Advanced Functional Materials, EarlyView.
Bioactive conductive Ti3C2Tx‐Ce hydrogels with with scavenging ROS and alleviating neuronal mitochondrial dysfunction are exploited for SCI treatment. This functionality is attributed to interfacial activation modification of Ti3C2Tx with Ce3+ ions to in‐situ form Ce(OH)x‐mediated protective layer, which is beneficial to enabling stable intracellular ...
Weikang Wang, Qing Liu, Ang Lv, Yabin Lin, Jiawei Chen, Ning Ding, Chunlei Zhang, Shuai Zhou, Bo Yuan, Weiwei Zhao, Liming Li, Luping Zhang, Fei Huang   +12 more
wiley   +1 more source

Renal function and histology after acute hemorrhage in rats under dexmedetomidine action Função e histologia renais após hemorragia aguda em ratos sob ação da dexmedetomidina

Acta Cirúrgica Brasileira, 2007
PURPOSE: About 50 % of indications for dialysis in acute renal failure are related to problems originated during the perioperative period. Intraoperative hemodynamic changes lead to renal vasoconstriction and hypoperfusion.
Marco Aurelio Marangoni, Alex Hausch, Pedro Thadeu Galvão Vianna, José Reinaldo Cerqueira Braz, Rosa Marlene Viero, Yara Marcondes Machado Castiglia   +5 more
doaj   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Investigations of the effects on the blood glucose levels of surgery and general anaesthesia with xylazine -ketamine and xylazine-pentobarbital sodium in healthy dogs [PDF]

Eurasian Journal of Veterinary Sciences
In this study, the effects of surgery and general anaesthesia that is with xylazine -ketamine hydrochloride and xylazine-pentobarbital sodium used commonly in carnivore, on the blood glucose levels, were investigated.
Celal İzci, Ali Muhtar Tiftik, Yılmaz Koç, Mustafa Arıcan   +3 more
doaj  

Effect of Sleep-improvement and Mechanism of Yanwo Ejiao Compound in Mice

Shipin gongye ke-ji
Objective: To evaluate improvement of sleep function and mechanism of Yanwo Ejiao compound in mice. Methods: Balb-c mice were randomly assigned to five groups: A blank control group, a positive drug group, and three Yanwo Ejiao compound groups receiving ...
Haiyun ZHENG, Zhigang WANG, Shaonan WANG, Bin WANG   +3 more
doaj   +1 more source

Evaluation of the Sleep-Prolonging Effect of Lagenaria vulgaris and Cucurbita pepo Extracts on Pentobarbital-Induced Sleep and Possible Mechanisms of Action

Medicina, 2018
Introduction: Sleeplessness is the most common sleep disorder. In this study, the hypnotic effect of macerated (HAME) and soxhlet (HASE) extract of Lagenaria vulgaris (fruit and seed) and Cucurbita pepo (fruit) were studied in mice. Methods: Extracts and
Vafa Baradaran Rahimi, Vahid Reza Askari, Amineh Sadat Tajani, Azar Hosseini, Hassan Rakhshandeh   +4 more
doaj   +1 more source

Renal Sodium Handling under Prolonged Pentobarbital Anesthesia

Experimental Biology and Medicine, 1951
Summary and ConclusionsThe influence of prolonged light surgical anesthesia with sodium pentobarbital on the renal tubular sodium reabsorptive ability was investigated in dogs initially given 50 cc per kg of isotonic saline by stomach tube. During time intervals averaging 5 hours, the tubules continued to reabsorb an average of 98.75% of the filtered ...
E E, SELKURT, K F, GLAUSER
openaire   +2 more sources