Results 81 to 90 of about 2,890 (209)

Efficacy and Safety of Linaclotide as an Adjunct to Polyethylene Glycol in Bowel Preparation: A Meta‐Analysis

Journal of Digestive Diseases, Volume 26, Issue 7-8, Page 318-333, July-August 2025.
Linaclotide combined with low‐volume polyethylene glycol (PEG) offers comparable bowel‐cleansing efficacy to traditional high‐volume PEG regimen while improving patient tolerability. Key benefits include higher segmental Boston Bowel Preparation Scale (BBPS) scores, reduced adverse events, and increased willingness to repeat the colonoscopic procedure,
Muhammad Shahzil, Fariha Hasan, Ali Akram Qureshi, Zainab Jamil, Talha Kashif, Muhammad Saad Faisal, Taha Bin Arif, Ammad Javaid Chaudhary, Umer Farooq, Hassam Ali, John M. Levenick   +10 more
wiley   +1 more source

Effectiveness and Safety of Oral Emulsion of Liquid Paraffin, Milk of Magnesia, and Sodium Picosulfate in the Management of Constipation Symptoms in Postanorectal Surgical Patients: A Prospective, Single-arm, Multi-center, Open-label Study

Indian Journal of Colo-Rectal Surgery
Background: This study aimed to evaluate the effectiveness and safety of oral emulsion containing milk of magnesia, liquid paraffin, and sodium picosulphate in treating constipation in Indian patients postanorectal surgery.
Pravin Padmakumar Gore, Suraj Kumar Pattnayak, Sreejoy Patnaik, Praveen Sharma, Jejoe Karankumar, Shivani Acharya   +5 more
doaj   +1 more source

Efficacy, safety, and tolerability of a ready-to-drink bowel preparation: subanalysis by age from a phase III, assessor-blinded study

Therapeutic Advances in Gastroenterology, 2020
Background: The incidence and mortality of colorectal cancer (CRC) increase with age and, therefore, it is recommended that adults undergo regular CRC screening, ideally by colonoscopy, with some new guidelines recommending screening begin at 45 years ...
Lawrence Hookey, Gerald Bertiger, Kenneth Lee Johnson, Mena Boules, Masakazu Ando, David N. Dahdal   +5 more
doaj   +1 more source

Hyponatremic Coma after Bowel Preparation

European Journal of Case Reports in Internal Medicine, 2019
Introduction: Colonoscopy is a useful tool in modern medicine and is increasingly employed for both diagnostic and treatment purposes. However, bowel preparations can cause electrolyte imbalance, with the risk apparently related to the type of bowel ...
João Costelha, Rita Dias, Carla Teixeira, Irene Aragão   +3 more
doaj   +1 more source

The Visibility and Performance of Small Bowel Video Capsule Endoscopy With and Without Pre‐Procedural Purge Preparation in the Same Patients

Journal of Gastroenterology and Hepatology, Volume 40, Issue 6, Page 1485-1491, June 2025.
ABSTRACT Background Small bowel (SB) video capsule endoscopy (VCE) is an established diagnostic tool for the investigation of SB pathologies. Despite clinical studies and a few meta‐analyses, an area of continuing controversy is the role of pre‐procedural bowel preparation.
Reuma Margalit Yehuda, Yana Davidov, Limor Selinger, Bella Ungar, Adi Lahat, Doron Yablecovitch, Sandra Neuman, Uri Kopylov, Shomron Ben Horin, Rami Eliakim, For the Israeli IBD Research Nucleus (IIRN)   +10 more
wiley   +1 more source

腸内菌由来Arylsulfate Sulfotransferaseに関する生化学的研究 [PDF]

, 1995
硫酸抱合反応は，種々の水酸基を有する化合物の解毒の主な経路である。この硫酸化を触媒する酵素としてsulfotransferaseが知られており，この酵素は，arylamine，phenol，steroidやbile acidなどの基質の違いにより分類されている。この酵素は硫酸基を3\u27-phosphoadenosine-5\u27-phosphosulfate(PAPS)からアルコール性あるいはフェノール性水酸基に転移する反応を触媒する。最近，同様な酵素が植物，Flaveriaからも見つかっている ...
今村 理佐
core   +1 more source

Assessment of Lubiprostone as an Adjunct Therapy for Bowel Preparation in Colonoscopy: A Meta‐Analysis of Randomized Controlled Trials

JGH Open, Volume 9, Issue 5, May 2025.
ABSTRACT Introduction The quality of bowel preparation has a significant impact on the success of colonoscopy. Currently, osmotically balanced polyethylene glycol electrolyte (PEG‐E) solutions are most commonly used for bowel preparation. Recently, lubiprostone (LBP) has been considered a potentially effective adjunct to PEG.
Fariha Hasan, Muhammad Shahzil, Ayesha Liaquat, Fatima Farooqi, Avneet Singh, Alexander Garcia, Muhammad Yafaa Naveed Chaudhary, Dushyant Singh Dahiya, Tanay‐Veer Gandhi, Andrew Alabd, Rachel Frank   +10 more
wiley   +1 more source

Comparison of propofol‐based sedation and midazolam sedation in pediatric bidirectional endoscopy conducted by pediatric gastroenterologists

DEN Open, Volume 5, Issue 1, April 2025.
Abstract Objectives The effectiveness and safety of propofol‐based sedation and midazolam sedation in pediatric bidirectional endoscopy were compared. Methods We retrospectively analyzed the cases of pediatric patients (≤15 years old) who had undergone bidirectional endoscopy, esophagogastroduodenoscopy, and colonoscopy by pediatric gastroenterologists.
Takahiro Kudo, Satomi Nishimoto, Ichitaro Horiuchi, Shingo Kurasawa, Satoshi Ukai, Akira Horiuchi   +5 more
wiley   +1 more source

Influence of atomic bonds on the properties of the laxative drug sodium picosulphate

Heliyon, 2016
In this work, the influence of the different S═O, S−O, N⋯H, O⋯H, Na⋯O bonds present in the structures of the powerful laxative drug, sodium picosulphate in gas and aqueous solution phases were studied combining the density functional theory (DFT ...
Davide Romani, Isabel Salas Tonello, Silvia Antonia Brandán   +2 more
doaj   +1 more source

What Patient Related Factors Negatively Impact Patient or Procedure Outcomes in Screening Colonoscopy? [PDF]

, 2012
The success of colonoscopy in early detection and treatment of colonic lesions depends upon adequate bowel preparation. This study addresses factors related to the adequacy of bowel preparation for colonoscopy with a focus on patient factors including ...
Truett, Rebecca
core   +1 more source