Results 61 to 70 of about 1,764,609 (301)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Are Reductions in Population Sodium Intake Achievable? [PDF]

Nutrients, 2014
The vast majority of Americans consume too much sodium, primarily from packaged and restaurant foods. The evidence linking sodium intake with direct health outcomes indicates a positive relationship between higher levels of sodium intake and cardiovascular disease risk, consistent with the relationship between sodium intake and blood pressure.
Levings, Jessica L., Cogswell, Mary E., Gunn, Janelle Peralez   +2 more
openaire   +2 more sources

Uptake and cytotoxicity of citrate-coated gold nanospheres : comparative studies on human endothelial and epithelial cells [PDF]

, 2012
The use of gold nanoparticles (AuNPs) for diagnostic applications and for drug and gene-delivery is currently under intensive investigation. For such applications, biocompatibility and the absence of cytotoxicity of AuNPs is essential. Although generally
Couraud, Pierre-Olivier, Freese, Christian, Gibson, Matthew I., Kirkpatrick, C. J. (C. James), Romero, Ignacio A., Uboldi, Chiara, Unger, Ronald E., Weksler, Babette B.   +7 more
core   +7 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Feasibility and antihypertensive effect of replacing regular salt with mineral salt -rich in magnesium and potassium- in subjects with mildly elevated blood pressure

Nutrition Journal, 2011
Background High salt intake is linked to hypertension whereas a restriction of dietary salt lowers blood pressure (BP). Substituting potassium and/or magnesium salts for sodium chloride (NaCl) may enhance the feasibility of salt restriction and lower ...
Sarkkinen Essi S, Kastarinen Mika J, Niskanen Tarja H, Karjalainen Pia H, Venäläinen Taisa M, Udani Jay K, Niskanen Leo K   +6 more
doaj   +1 more source

Impact of foods with health logo on ssaturated fat, sodium and sugar intake of young Dutch adults [PDF]

Objective Health logos are introduced to distinguish foods with ‘healthier’ nutrient composition from regular foods. In the present study, we evaluated the effects of changed food compositions according to health logo criteria on the intake of saturated ...
Bulder, A., Donkersgoed, A., van, Klaveren, J.D., van, Roodenburg, A., Temme, E.H.M., Voet, H., van der   +5 more
core   +3 more sources

Turbulent Conductivity Measurements In A Spherical Liquid Sodium Flow [PDF]

, 2001
We report the first measurement of a reduction in the conductivity of liquid sodium due to turbulence in a spherical flow (the beta effect). The sodium is contained in a 0.15 m diameter sphere, typical flow speeds are about 1 m/s, and magnetic Reynold ...
Brown, Michael R., Reighard, Amy, , \u2701   +1 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Projected impact of a sodium consumption reduction initiative in Argentina: an analysis from the CVD policy model--Argentina. [PDF]

PLoS ONE, 2013
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death in adults in Argentina. Sodium reduction policies targeting processed foods were implemented in 2011 in Argentina, but the impact has not been evaluated. The aims of this study are to
Jonatan Konfino, Tekeshe A Mekonnen, Pamela G Coxson, Daniel Ferrante, Kirsten Bibbins-Domingo   +4 more
doaj   +1 more source

Solvation agent for disulfide precipitates from inhibited glycol-water solutions [PDF]

, 1971
Small additions /0.01 percent or less/ of triethanoloamine sodium sulfite adduct to mercapto benzothiazole inhibited glycol water heat transfer solutions containing disulfide precipitate produce marked reduction in amount of precipitate. Adduct is useful
Taylor, M. F.
core   +1 more source