Results 31 to 40 of about 9,017 (154)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, Volume 38, Issue 26, 8 May 2026.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

A comparison of hemodynamic effects of Midazolam and Thiopental in induction of anesthesia

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2000
Objective: Although thiopental sodium (Nesdonal) is an almost ideal drug for induction of anesthesia, but it mostly cause hemodynamic changes such as hypotension.
E Alijan Poor, SM Rabiei, S Mir Shekari
doaj  

Pharmacological Evaluation of Methanolic Fruit Extract of Lannea coromandelica: Antioxidant, Cytotoxic, Antidiabetic, Antibacterial, Anti‐Inflammatory, and Sedative Activities

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Phytochemical investigation of Lannea coromandelica through GC–MS and in silico analysis revealed diverse bioactive compounds with promising pharmacological potential. Integrated in vitro and in vivo assays demonstrated significant antioxidant, antidiabetic, antibacterial, anti‐inflammatory, and sedative activities, supporting its therapeutic relevance.
Priota Islam Meem   +7 more
wiley   +1 more source

Comparison of recovery duration of Propofol and Thiopental Sodium in ECT

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2005
Background and objective: Thiopental sodium is not and ideal intravenous drug for inducing general anesthesia and compared to intravenous anesthetic drugs like propofol has a long standing recovery time.
H Ale Reza   +5 more
doaj  

Impact of Various Sedation Methods in Patients with Acute Severe Brain Injury on Lipid Peroxidation

open access: yesОбщая реаниматология, 2008
Objective: to study the impact of various sedation methods on lipid peroxidation in patients with acute severe brain injury. Subjects and methods. For this, 44 victims with this condition were examined.
V. V. Unzhakov, S. K. Sukhotin
doaj   +1 more source

Melatonin and Quercetin Co‐Treatment Attenuates Hepatic Damage in Diabetic Rats by Mitigating Oxidative Stress and Inflammation

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 5, May 2026.
Quercetin and melatonin, alone or combined, effectively protect the liver in diabetic rats. The antioxidants reduce hyperglycemia, oxidative stress, and inflammation, preventing hepatic damage. ABSTRACT Liver complications in diabetes are very common, contributing to a high mortality rate, making it essential to develop strategies to minimize this ...
Érique Ricardo Alves   +10 more
wiley   +1 more source

COMPARATIVE ANAESTHETIC EFFICACY OF PROPOFOL, THIOPENTAL SODIUM AND COMBINATION OF PROPOFOL WITH KETAMINE HYDROCHLORIDE IN DOGS [PDF]

open access: yesPakistan Veterinary Journal, 2009
The present study was undertaken to determine the comparative efficacy of propofol alone at two dosages, thiopental sodium and propofol in combination with ketamine hydrochloride in dogs. For this purpose, 24 healthy stray dogs were randomly divided into
N. MUHAMMAD, M. A. ZAFAR, G. MUHAMMAD, M. Z. MASOOD, A. MANZOOR AND I. SARFARAZ
doaj  

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

LIDOCAINE / THIOPENTAL FOR ANAESTHETIC INDUCTION IN DONKEYS [PDF]

open access: yesAssiut Veterinary Medical Journal, 1991
Lidocaine Hel (2% solution) was administered intravenously before induction of anaesthesia with thiopental sodium. Injection of the local analgesic in a dose rate of 2 mg/kg B.Wt not only promoted a smooth induction, but also improved recovery. While the
H.A. YOUSSEF, I.H. AHMED, F.M. MAKADY
doaj   +1 more source

Cytological and Pathological Characterization of Canine Neoplasm in and Around Bishoftu, Ethiopia

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study characterizes dog tumours cytologically and histopathologically in and around Bishoftu town. Mammary gland adenocarcinoma, papillary mammary adenocarcinoma, carcinoma–mixed type, Sertoli cell tumour, atypical anal sac adenocarcinoma, fibrothecoma, cutaneous mast cell tumour and transmissible venereal tumour were the tumours identified and ...
Mesfin Mathewos   +2 more
wiley   +1 more source

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