Thiopental sodium loaded solid lipid nano-particles attenuates obesity-induced cardiac dysfunction and cardiac hypertrophy via inactivation of inflammatory pathway. [PDF]
This work evaluates solid lipid nanoparticles of thiopental sodium against obesity-induced cardiac dysfunction and hypertrophy and explores the possible mechanism of action.
Zhu C +7 more
europepmc +3 more sources
A Pilot Study of Cerebral and Hemodynamic Changes During Sedation with Low Dose of Thiopental Sodium or Propofol in Patients with Acute Brain Injury. [PDF]
Background: One of the most important therapeutic maneuvers in head injury patients is to maintain Intracranial Pressure (ICP) and Cerebral Perfusion Pressure (CPP) within normal levels.
Yaghoobi S, Khezri MB, Alamouti AM.
europepmc +2 more sources
The Effects of Propofol and Thiopental on Nitric Oxide Production and Release in Erythrocytes. [PDF]
Background: Hypotension is a common adverse effect associated with the use of propofol and sodium thiopental. The objective of this study was to examine the impact of thiopental and propofol on erythrocyte (RBC) nitric oxide (NO) synthase activity and ...
Arslan U +11 more
europepmc +2 more sources
Exploring Cognitive and Affective Outcomes Following Bilateral 6-Hydroxydopamine Lesions of the Substance Nigra or Striatum in Rats. [PDF]
Our results demonstrate massive degeneration of tyrosine hydroxylase‐immunoreactive neurons was observed in the SNpc, striatum, and ventral tegmental area with 6‐OHDA infusions in either the SNpc or striatum. Rats administered 6‐OHDA to the SNpc exhibited cognitive impairments, anxiety‐like behaviors, and impacted the maturation of newborn hippocampal ...
de Mattos BA +4 more
europepmc +2 more sources
Bee Bread Protects Small Intestinal Mucosa and Modulates Local Redox Responses in Streptozotocin-Induced Diabetic Rats. [PDF]
In streptozotocin‐induced diabetic rats, bee bread supplementation attenuated diabetes‐associated intestinal mucosal alterations and modulated local redox responses. Treatment reduced blood glucose levels and influenced the immunoreactivity patterns of Mn‐SOD and CAT, supporting a protective role of bee bread in maintaining small intestinal mucosal ...
Sari EK +4 more
europepmc +2 more sources
Sedative potential of palmatine chloride in thiopental sodium-induced chicks: evidence from in vivo and in Silico studies. [PDF]
The aim of this study is to assess the sedative impact of palmatine chloride (PME) in thiopental sodium-induced sleeping chicks and its underlying molecular mechanism by using in vivo and in silico approaches.
Nun FK +7 more
europepmc +2 more sources
Anaesthesiologist's role in hypnotic abreaction - Sodium thiopental revisited. [PDF]
Sivapurapu V, Nyima T.
europepmc +2 more sources
Aim: The aim of the present study was to compare the pain intensity due to intravenous injection of sodium thiopental, propofol, diazepam, and etomidate during the induction of general anesthesia.
Naeem Abdi +7 more
doaj +1 more source
The effect of sodium thiopental as a GABA mimetic drug in neonatal period on expression of GAD65 and GAD67 genes in hippocampus of newborn and adult male rats [PDF]
Objective(s): Development of the nervous system in human and most animals is continued after the birth. Critical role of this period in generation and specialization of the neuronal circuits is confirmed in numerous studies.
Masoud Naseri, Abbas Parham, Ali Moghimi
doaj +1 more source
Schistosoma mansoni: effects of anesthetics and antimonial drugs on worm shift in the mouse
Mice experimentally infected with Schistosoma mansoni were injected with sodium thiopental or sodium antimonyl gluconate (Triostib R), or submitted to halothane inhalation, with or without a previous injection of thiopental.
José Renan da Cunha-Melo +1 more
doaj +1 more source

