Thiopental sodium loaded solid lipid nano-particles attenuates obesity-induced cardiac dysfunction and cardiac hypertrophy via inactivation of inflammatory pathway [PDF]
This work evaluates solid lipid nanoparticles of thiopental sodium against obesity-induced cardiac dysfunction and hypertrophy and explores the possible mechanism of action.
Canzhan Zhu +7 more
doaj +2 more sources
A Pilot Study of Cerebral and Hemodynamic Changes During Sedation with Low Dose of Thiopental Sodium or Propofol in Patients with Acute Brain Injury [PDF]
Background: One of the most important therapeutic maneuvers in head injury patients is to maintain Intracranial Pressure (ICP) and Cerebral Perfusion Pressure (CPP) within normal levels.
Siamak Yaghoobi +2 more
doaj +2 more sources
The Effects of Propofol and Thiopental on Nitric Oxide Production and Release in Erythrocytes [PDF]
Background: Hypotension is a common adverse effect associated with the use of propofol and sodium thiopental. The objective of this study was to examine the impact of thiopental and propofol on erythrocyte (RBC) nitric oxide (NO) synthase activity and ...
Ulku Arslan +11 more
doaj +2 more sources
Propofol-Related Infusion Syndrome in Paediatrics-Cautious Consideration or Considered Caution? Case Report. [PDF]
Journal of Paediatrics and Child Health, Volume 62, Issue 6, Page 1075-1080, June 2026.
Stokes MA +5 more
europepmc +2 more sources
Gallic Acid-Mediated Enhancement of Diazepam-Induced Sedation via GABA<sub>A</sub> Receptor Modulation: In Vivo and In Silico Evaluation. [PDF]
Gallic acid (GA) dose‐dependently reduced sleep latency and prolonged sleep duration in thiopental sodium‐induced mice, with synergistic effects when combined with diazepam. Molecular docking revealed GA's higher binding affinity (−9.8 kcal/mol) to GABAA receptor (α1 and β2 subunits) than diazepam (−8.4 kcal/mol), suggesting GABAergic potential ...
Yana NT +14 more
europepmc +2 more sources
Rapid recovery after intrathecal dexamethasone in FIRES. [PDF]
Epileptic Disorders, Volume 28, Issue 3, Page 884-887, June 2026.
Nico JF +8 more
europepmc +2 more sources
Sedative potential of palmatine chloride in thiopental sodium-induced chicks: evidence from in vivo and in Silico studies [PDF]
The aim of this study is to assess the sedative impact of palmatine chloride (PME) in thiopental sodium-induced sleeping chicks and its underlying molecular mechanism by using in vivo and in silico approaches.
Feroz Khan Nun +7 more
doaj +2 more sources
Hemodynamic Responses to Etomidate Versus Ketamine-Thiopental Sodium Combination for Anesthetic Induction in Coronary Artery Bypass Graft Surgery Patients with Low Ejection Fraction: A Double-Blind, Randomized, Clinical Trial [PDF]
Background: During induction of anesthesia and intubation, hemodynamic changes are very important; especially in patients with coronary artery disease (CAD) and left ventricular dysfunction.
Mohammad Reza Habibi +6 more
doaj +2 more sources
Aim: The aim of the present study was to compare the pain intensity due to intravenous injection of sodium thiopental, propofol, diazepam, and etomidate during the induction of general anesthesia.
Naeem Abdi +7 more
doaj +1 more source
The effect of sodium thiopental as a GABA mimetic drug in neonatal period on expression of GAD65 and GAD67 genes in hippocampus of newborn and adult male rats [PDF]
Objective(s): Development of the nervous system in human and most animals is continued after the birth. Critical role of this period in generation and specialization of the neuronal circuits is confirmed in numerous studies.
Masoud Naseri, Abbas Parham, Ali Moghimi
doaj +1 more source

