Results 31 to 40 of about 15,865 (202)

Transcriptomic analysis reveals lipid metabolism and macrophage involvement associated with nintedanib treatment in a rat bleomycin model

British Journal of Pharmacology, EarlyView.
In this study, nintedanib reduced lung fibrosis in a rat double‐hit bleomycin‐induced model. Transcriptomic analysis revealed two key gene signatures related to the effect of the molecule: one involving mesenchymal cells affecting known fibrotic pathways and another linking mainly macrophages to lipid metabolism.
Martina Bonatti, Vanessa Pitozzi, Paola Caruso, Silvia Pontis, Maria Gloria Pittelli, Caterina Frati, Denise Madeddu, Federico Quaini, Costanza Anna Maria Lagrasta, Ilaria Minato, Emanuela Bocchi, Maurizio Civelli, Gino Villetti, Marcello Trevisani, Barbara Montanini   +14 more
wiley   +1 more source

Effect of propofol versus sodium thiopental on electroconvulsive therapy in major depressive disorder, a randomized double-blind controlled clinical trial

Psychiatry and Clinical Psychopharmacology, 2021
Objectives: To compare propofol and sodium thiopental as anesthetic agents for electroconvulsive therapy (ECT) in major depression with respect to clinical effect.
Taner Purtuloğlu, Barbaros Özdemir, Murat Erdem, Süleyman Deniz, Adem Balikci, Gazi Ünlü, Taner Öznur   +6 more
doaj  

Balancer‐assisted sling recovery of critical equine patients after general anaesthesia

Equine Veterinary Education, EarlyView.
Summary Background Traditional sling‐based systems to assist horses during recovery from general anaesthesia (GA) could be improved by adding a balancer to obtain a dynamic weight relief. Objectives To evaluate the applicability of a novel balancer‐assisted sling system during recovery of horses after GA and to report initial experiences with high‐risk
J. Kuhlmann, C. Spadavecchia, C. Koch
wiley   +1 more source

To compare the blood pressure and heart rate during course of various types of anesthesia in wistar rat: A novel experiences

Asian Journal of Medical Sciences, 2018
Background: Rats are commonly used animals in development of newer drugs, rectification of toxicity and to record the various alterations in physiological parameters following pharmacological and non pharmacological interventions.
Jagdish Narayan , Pradeep Kumar , Ankit Gupta, Sunita Tiwari   +3 more
doaj   +1 more source

Too Sick to Be Executed: Shocking Punishment and the Brain [PDF]

, 2016
Capital punishment, to be lawfully delivered, must occur without needless cruelty. Cruelty, defined in the setting of punishment, will naturally evolve with the maturation of civil society.
Zivot, Joel
core   +1 more source

Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]

, 2015
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR, Brosnan, RJ, Fletcher, DJ, Holliday, TA, Kass, PH, LeCouteur, RA, Steffey, EP, Tharp, B, Williams, DC   +8 more
core   +1 more source

Impact comparison of ketamine and sodium thiopental on anesthesia during electroconvulsive therapy in major depression patients with drug-resistant; a double-blind randomized clinical trial

Annals of Cardiac Anaesthesia, 2015
Background: Electroconvulsive therapy (ECT) is one of the available and the most effective therapies for the treatment of resistant depression. Considering the crucial role of seizure duration on therapeutic response in patients treated with ECT, this ...
B Salehi, A Mohammadbeigi, A R Kamali, M R Taheri-Nejad, I Moshiri   +4 more
doaj   +1 more source

Anatomy of corpus callosum in prenatally malnourished rats [PDF]

, 2012
Indexación: Web of Science; ScieloThe effect of prenatal malnutrition on the anatomy of the corpus callosum was assessed in adult rats (45-52 days old).
Aboitiz, Francisco, Flores, Osvaldo, Gil, Julio, Gimeno, Miguel, Hernandez, Alejandro, Laborda, Jesús, Morgan, Carlos, Olivares, Ricardo, Ortiz, Alexis, Pérez, Hernan, Soto-Moyano, Ruben   +10 more
core   +2 more sources

Pharmacological Evaluation of Methanolic Fruit Extract of Lannea coromandelica: Antioxidant, Cytotoxic, Antidiabetic, Antibacterial, Anti‐Inflammatory, and Sedative Activities

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Phytochemical investigation of Lannea coromandelica through GC–MS and in silico analysis revealed diverse bioactive compounds with promising pharmacological potential. Integrated in vitro and in vivo assays demonstrated significant antioxidant, antidiabetic, antibacterial, anti‐inflammatory, and sedative activities, supporting its therapeutic relevance.
Priota Islam Meem, Zobayed Islam, Nazmul Hasan Eshaque, Md. Jahirul Islam Mamun, Khurram Murad Mojidee, Mohammad Badrudduja, Amit Kumar Dam, S. M. Moazzem Hossen   +7 more
wiley   +1 more source

Melatonin and Quercetin Co‐Treatment Attenuates Hepatic Damage in Diabetic Rats by Mitigating Oxidative Stress and Inflammation

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 5, May 2026.
Quercetin and melatonin, alone or combined, effectively protect the liver in diabetic rats. The antioxidants reduce hyperglycemia, oxidative stress, and inflammation, preventing hepatic damage. ABSTRACT Liver complications in diabetes are very common, contributing to a high mortality rate, making it essential to develop strategies to minimize this ...
Érique Ricardo Alves, Jaiurte Gomes Martins da Silva, Ismaela Maria Ferreira de Melo, Laís Caroline da Silva Santos, Marcelle Mariana Sales de França, Clovis Lapa Neto, Vanessa Bischoff Medina, Francisco de Assis Leite Souza, Leucio Duarte Vieira, Álvaro Aguiar Coelho Teixeira, Valéria Wanderley Teixeira   +10 more
wiley   +1 more source