Results 51 to 60 of about 9,040 (154)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, Volume 38, Issue 26, 8 May 2026.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

A Comparison of Depth of Anesthesia and Hemodynamic Variables with Sodium Thiopental and Propofol as Induction Agents for Cesarean Section

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2012
BACKGROUND AND OBJECTIVE: More than 30% of deliveries are carried out by cesarean section. Spinal anesthesia is the routine and safe method but, in some situations, general anesthesia is selected instead.
SM Rabiee,   +4 more
doaj  

Pharmacological Evaluation of Methanolic Fruit Extract of Lannea coromandelica: Antioxidant, Cytotoxic, Antidiabetic, Antibacterial, Anti‐Inflammatory, and Sedative Activities

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Phytochemical investigation of Lannea coromandelica through GC–MS and in silico analysis revealed diverse bioactive compounds with promising pharmacological potential. Integrated in vitro and in vivo assays demonstrated significant antioxidant, antidiabetic, antibacterial, anti‐inflammatory, and sedative activities, supporting its therapeutic relevance.
Priota Islam Meem   +7 more
wiley   +1 more source

Investigation of in vivo neuropharmacological effect of Alpinia nigra leaf extract

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2014
Objective: To analyze in vivo neuro-pharmacological effects of Alpinia nigra as anxiety is a particular form of behavioral inhibition that occurs in response to novel environmental events.
Farjana Sharmen   +5 more
doaj   +1 more source

Violation of renal transport of sodium ions under conditions of skeletal trauma of different sevsrity, complicated by blood loss

open access: yesJournal of Education, Health and Sport, 2019
Objective: to find out the features of renal transport of sodium ions in the early period after skeletal trauma of different severity, complicated by blood loss.
V. V. Kovalov   +2 more
doaj   +3 more sources

Rectal Thiopental versus Intramuscular Ketamine in Pediatric Procedural Sedation and Analgesia; a Randomized Clinical Trial

open access: yesEmergency, 2015
Introduction: Physicians frequently deal with procedures which require sedation of pediatric patients. Laceration repair is one of them. No study has been performed regarding the comparison between induction of sedation with sodium thiopental and ...
Reza Azizkhani   +3 more
doaj  

HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHY

open access: yesВестник анестезиологии и реаниматологии, 2019
From the safety point of view, procedural sedation results in fairly frequent complications, typical of the anesthetics being used.The objective: to study the hemodynamics, gas exchange and the character of complications (respiratory disorders, agitation)
R. V. Zhdanov, E. V. Grigoriev
doaj   +1 more source

LIDOCAINE'S CONTROVERSY [PDF]

open access: yesActa Medica Iranica, 1993
In a cross section of the patients scheduled for various operations, the plausability of lidocaine as an induction agent is studied and described. The results were dismaying suggesting, henceforth, that as an induction agent, lidocaine altogether fails ...
Zahid Hussain Khan
doaj  

Comparison of Recovery Time and Complications During the Use of Etomidate and Thiopental Sodium in Anesthesia in Children for Electroconvulsive Therapy; A Double Blind Randomized Clinical Trial

open access: yesArchives of Anesthesia and Critical Care, 2017
Background: Electroconvulsive therapy (ECT) is usually given to people with severe depression which has not responded to other forms of treatment such as anti-depressants.
Behzad Nazemroaya, Elham Babaei
doaj  

Home - About - Disclaimer - Privacy