Results 71 to 80 of about 2,097,671 (275)

Neurological Soft Signs and Psychopathology in Chronic Schizophrenia: A Cross-Sectional Study in Three Age Groups

Frontiers in Psychiatry, 2018
As established in a wealth of studies subtle motor and sensory neurological abnormalities or neurological soft signs (NSS) are frequently found in patients with schizophrenia at any stage of their illness.
Christina J. Herold, Marc M. Lässer, Ulrich Wilhelm Seidl, Dusan Hirjak, Philipp A. Thomann, Johannes Schröder   +5 more
doaj   +1 more source

Neurological Soft Signs and Post-Traumatic Stress Disorder: A Biomarker of Severity?

Frontiers in Psychiatry, 2020
BackgroundThe psychophysiological changes for individual suffering from chronic post-traumatic stress disorder (PTSD) raise to the questions of how facilitate recovery and return to work.
Célia Belrose, Célia Belrose, Célia Belrose, Anais Duffaud, Anais Duffaud, Elsa Rakotoarison, Catherine Faget, Philippe Raynaud, Philippe Raynaud, Frédéric Dutheil, Frédéric Dutheil, Léa Boyer, Jean-Baptiste Billaud, Marion Trousselard, Marion Trousselard, Marion Trousselard   +15 more
doaj   +1 more source

Neurological soft signs in prodromal patients

, 1998
Neurological soft signs in prodromal ...
W Brewer (13452606), C Pantelis (10229780), P McGorry (13312743), Alison Yung (13100928), D Velakoulis (10456577)   +4 more
core  

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Soft Neurological Signs in Patients with Chronic Psychiatric Illness in a Rehabilitation Center: A Cross-sectional Study [PDF]

Indian Journal of Private Psychiatry
Background: Numerous neurological soft signs (NSS), which act as a measure of illness severity, are frequently experienced by the susceptible group of people with chronic mental illnesses. An individual's social functioning may be greatly impacted by NSS,
Bhanu Dahiya, Shashwath Sathyanath, Anil Kakunje   +2 more
doaj   +1 more source

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

Advanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia, Siyu Li, Songming Tang, Keju Gu, Shengquan Chen   +4 more
wiley   +1 more source

Neurological soft signs in Tunisian patients with first-episode psychosis and relation with cannabis use

Annals of General Psychiatry, 2017
Background Neurological soft signs (NSS) are minor non-localizing neurological abnormalities that are conceptualized as neurodevelopmental markers that mediate the biological risk for psychosis.
Ahmed Mhalla, Bochra Ben Mohamed, Christoph U. Correll, Badii Amamou, Anouar Mechri, Lotfi Gaha   +5 more
doaj   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

Neurological soft signs and EEG findings in children and adolescents with Gilles de la Tourette syndrome

The Turkish Journal of Pediatrics, 2000
Gilles de la Tourette syndrome (GTS) is a childhood-onset neuropsychiatric disorder, characterized by multiple motor and vocal tics. The presence of EEG abnormalities and neurological soft signs are reported in patients with GTS.
Z B Semerci
doaj  

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

Advanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai, Jikuang Zhao, Chang Xue, Kailei Xu, Liang Yong, Zhuangwei Zhang, Yi Huang, Jianwei Shuai, Xianzhen Chen, Sheng Nie, Junpeng Xu   +10 more
wiley   +1 more source