Results 51 to 60 of about 9,157,831 (331)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Fuzzy Supernova Templates I: Classification

, 2009
Modern supernova (SN) surveys are now uncovering stellar explosions at rates that far surpass what the world's spectroscopic resources can handle. In order to make full use of these SN datasets, it is necessary to use analysis methods that depend only on
Aldering, Barbary, Barris, Blondin, Cappellaro, Di Carlo, Dubois, Dubois, Garnavich, George, Goldhaber, Gregory, Gänsicke, Hamacher, Hamuy, Hatano, Hicken, Holtzman, Homeier, Howell, Hsiao, Jha, Jha, Jha, John L. Tonry, Johnson, Klir, Krisciunas, Krisciunas, Krisciunas, Kuznetsova, Lair, Leonard, Lewis, Lira, Meikle, Miknaitis, Nugent, Patat, Perlmutter, Poznanski, Qiu, Reindl, Riess, Riess, Riess, Sako, Sollerman, Steven A. Rodney, Stritzinger, Sullivan, Suntzeff, Tonry, Tsvetkov, Tsvetkov, Wang, Wood-Vasey, Yokoo, Yoshii   +58 more
core   +1 more source

Characterization of soft stripe-domain deformations in Sm-C and Sm-C* liquid-crystal elastomers [PDF]

, 2008
The neoclassical model of Sm-C (and Sm-C*) elastomers developed by Warner and Adams predicts a class of “soft” (zero energy) deformations. We find and describe the full set of stripe domains—laminate structures in which the laminates alternate between ...
Bhattacharya, K., Biggins, J. S.
core   +2 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Geometric Soft Sets

Hittite Journal of Science & Engineering, 2017
Snew concept called geometric soft sets to present and analyze the geometrical, topological, oft sets are efficient tools to determine uncertainty in systems.
openaire   +5 more sources

Plithogenic Soft Set

Neutrosophic Sets and Systems, 2020
In 1995, Smarandache initiated the theory of neutrosophic set as new mathematical tool for handling problems involving imprecise, indeterminacy, and inconsistent data. Molodtsov initiated the theory of soft set as a new mathematical tool for dealing with uncertainties, which traditional mathematical tools cannot handle.
openaire   +2 more sources

ON SOFT LIFTS AND SOFT TRANSFORMATIONS INDUCED BY SOFT SETS [PDF]

International Journal of Pure and Apllied Mathematics, 2016
We introduced the notion of monotonic operation uF : P (X) → P (X) induced by AF , F ← in any soft set (F,X) (A ⊆ X) in [13]. In this paper, we also introduce the notions of soft lift and soft transformation induced by F←. We investigate properties for the notions. In particular, Theorem 3.14 and Theorem 3.15 are obtained.
Young Key Kim, Won Keun Min
openaire   +3 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Gating Artificial Neural Network Based Soft Sensor [PDF]

, 2008
This work proposes a novel approach to Soft Sensor modelling, where the Soft Sensor is built by a set of experts which are artificial neural networks with randomly generated topology.
Gabrys, Bogdan, Kadlec, Petr
core