Results 41 to 50 of about 1,158,111 (278)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Redefined soft relations and soft functions [PDF]

International Journal of Computational Intelligence Systems, 2015
Soft set theory, proposed by Molodtsov, has been regarded as an effective mathematical tool to deal with uncertainties. In this paper, the notion of soft relation is introduced which is a generalization of the notion of soft set relation, and some ...
Keyun Qin, Qiong Liu, Yang Xu
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Relations on FP-Soft Sets Applied to Decision Making Problems [PDF]

, 2014
In this work, we first define relations on the fuzzy parametrized soft sets and study their properties. We also give a decision making method based on these relations.
Deli, Irfan, Çağman, Naim
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Boolean Algebra of Soft Q-Sets in Soft Topological Spaces

Applied Computational Intelligence and Soft Computing, 2022
We define soft Q-sets as soft sets whose soft closure and soft interior are commutative. We show that the soft complement, soft closure, and soft interior of a soft Q-set are all soft Q-sets. We show that a soft subset K of a given soft topological space
Samer Al Ghour
doaj   +1 more source

soft sets, soft rough sets, soft pre-rough sets, information system, decision making

AIMS Mathematics, 2023
For any real $ \beta $ let $ H^2_\beta $ be the Hardy-Sobolev space on the unit disc $ {\mathbb D} $. $ H^2_\beta $ is a reproducing kernel Hilbert space and its reproducing kernel is bounded when $ \beta > 1/2 $. In this paper, we prove that $ C_{\varphi } $ has dense range in $ H_{\beta }^{2} $ if and only if the polynomials are dense in a certain
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

WEIGHTED NEUTROSOPHIC SOFT SETS APPROACH IN A MULTICRITERIA DECISION MAKING PROBLEM

Journal of New Theory, 2015
– The paramount importance of decision making problem in an imprecise environment is becoming very much significant in recent years. In this paper we have studied weighted neutrosophic soft sets which are a hybridization of neutrosophic sets with soft ...
Pabitra Kumar Maji
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source