Results 41 to 50 of about 8,148 (246)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Peptide OPTX-1 From Ornithodoros papillipes Tick Inhibits the pS273R Protease of African Swine Fever Virus

Frontiers in Microbiology, 2021
African swine fever virus (ASFV) is a large double-stranded DNA virus and causes high mortality in swine. ASFV can be transmitted by biological vectors, including soft ticks in genus Ornithodoros but not hard ticks.
Jingjing Wang, Jingjing Wang, Mengyao Ji, Bingqian Yuan, Anna Luo, Zhenyuan Jiang, Zhenyuan Jiang, Tengyu Zhu, Tengyu Zhu, Yang Liu, Yang Liu, Peter Muiruri Kamau, Lin Jin, Lin Jin, Ren Lai, Ren Lai, Ren Lai, Ren Lai   +17 more
doaj   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

Advanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni, Nitzan Letko Khait, Adam Forman, Edward A. Armstrong, Karim Fouad, Molly S. Shoichet   +5 more
wiley   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

Advanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar, Carlos Alejandro Jimenez‐Rodriguez, Railia Biktimirova, Ilka Hermes, Thomas Kurth, My Duyen Pham, Mikhail Tsurkan, Jens Friedrichs, Francis L. C. Morgan, Hans Kleemann, Olga Guskova, Uwe Freudenberg, Peter Fratzl, Carsten Werner, Christoph Tondera, Ivan R. Minev   +15 more
wiley   +1 more source

Influence of endosymbionts on the reproductive fitness of the tick Ornithodoros moubata

Peer Community Journal, 2023
Over the past decade, many studies have demonstrated the crucial role of the tick microbiome in tick biology. The soft tick Ornithodoros moubata is a hematophagous ectoparasite of Suidae, best known for transmitting the  African swine fever virus.
Taraveau, Florian, Pollet, Thomas, Duhayon, Maxime, Gardès, Laëtitia, Jourdan-Pineau, Hélène   +4 more
doaj   +1 more source

Double‐Sided Mechanical Interlocking Enables Soft‐Rigid Conductive Interfaces With a Record High Toughness for Flexible Electronics

Advanced Materials, EarlyView.
A double‐sided mechanical interlocking strategy is developed to create robust electrical contact between polymer electrode and metal interconnect. The fibrous structure enables formation of thread–hole adhesion, which only breaks under bulk failure and achieves a record high interfacial energy exceeding 730 J·m−2. This adhesion secures the integrity of
Gang Li, Minkun Cai, Chunyan Cao, Zengbai Ouyang, Hong Fu, Lingyu Zhao, Bingang Xu   +6 more
wiley   +1 more source

Seasonal distribution and faunistic of ticks in the Alashtar county (Lorestan Province), Iran

The Pan African Medical Journal, 2017
INTRODUCTION: Ticks are non-permanent obligate parasites that have considerable medical-veterinary and zoonosis importance. In this regard a study designed to investigate the distribution and fauna of ticks in the Alashtar county in Iran from April and ...
Behroz Davari, Firoz Nazari Alam, Hassan Nasirian, Mansour Nazari, Mohammad Abdigoudarzi, Aref Salehzadeh   +5 more
doaj   +1 more source

Differential Expression of Putative Ornithodoros turicata Defensins Mediated by Tick Feeding

Frontiers in Cellular and Infection Microbiology, 2020
Additional research on soft ticks in the family Argasidae is needed to bridge the knowledge gap relative to hard ticks of the family Ixodidae; especially, the molecular mechanisms of Ornithodoros biology.
Brittany A. Armstrong, Brittany A. Armstrong, Alexander R. Kneubehl, Alexander R. Kneubehl, Robert D. Mitchell, Aparna Krishnavajhala, Pete D. Teel, Adalberto A. Pérez de León, Job E. Lopez, Job E. Lopez   +9 more
doaj   +1 more source

Defensins as a promising class of tick antimicrobial peptides: a scoping review

Infectious Diseases of Poverty, 2022
Background Ticks are hematophagous parasites that transmit an extensive range of pathogens to their vertebrate hosts. Ticks can destroy invading microorganisms or alleviate infection via their rudimentary but orchestrated innate immune system ...
Jiahui Wu, Xia Zhou, Qiaoqiao Chen, Zhiqiang Chen, Jinyu Zhang, Lele Yang, Yuxuan Sun, Guohui Wang, Jianfeng Dai, Tingting Feng   +9 more
doaj   +1 more source

BioEISense: A Microfluidic Platform for Real‐Time Monitoring of Staphylococcus aureus Biofilm Formation and the Efficacy of Antibiofilm Agents

Advanced Materials Interfaces, EarlyView.
BioEISense is a microfluidic device with integrated impedance sensors, for real‐time, label‐free monitoring of S. aureus biofilms. In this study, the biofilm culture conditions were optimized to support sensitive and reproducible detection of biofilm formation and eradication under dynamic flow‐through conditions. The system was also validated for both
Jéssica Amorim, Laura Vesalainen, Loïc Dreano, Markus Haapala, Cristina D. Cruz, Päivi Tammela, Tiina M. Sikanen   +6 more
wiley   +1 more source