Results 21 to 30 of about 692,219 (243)
Distinctive ionic transport of freshly excised human epileptogenic brain tissue [PDF]
Applied Physics Letters, 119, 253701 (2021), 2022 Epileptogenic lesions have higher concentrations of sodium than does normal brain tissue. Such lesions are palpably recognized by a surgeon and then excised in order to eliminate epileptic seizures with their associated abnormal electrical behavior. Here we study the frequency-dependent electrical conductivities of lesion-laden tissues excised from the
arxiv +1 more source
Geometric signatures of tissue surface tension in a three-dimensional model of confluent tissue [PDF]
, 2021 In dense biological tissues, cell types performing different roles remain segregated by maintaining sharp interfaces. To better understand the mechanisms for such sharp compartmentalization, we study the effect of an imposed heterotypic tension at the interface between two distinct cell types in a fully 3D model for confluent tissues.
arxiv +1 more source
Towards real-time finite-strain anisotropic thermo-visco-elastodynamic analysis of soft tissues for thermal ablative therapy [PDF]
Computer Methods and Programs in Biomedicine, vol. 198, pp.
105789, 2021, 2020 Accurate and efficient prediction of soft tissue temperatures is essential to computer-assisted treatment systems for thermal ablation. It can be used to predict tissue temperatures and ablation volumes for personalised treatment planning and image-guided intervention.
arxiv +1 more source
Autonomous Soft Tissue Retraction Using Demonstration-Guided Reinforcement Learning [PDF]
arXiv, 2023 In the context of surgery, robots can provide substantial assistance by performing small, repetitive tasks such as suturing, needle exchange, and tissue retraction, thereby enabling surgeons to concentrate on more complex aspects of the procedure.
arxiv
Ultrasonic Estimation of Soft Tissue Visco Elastic Properties [PDF]
arXiv, 2022 Conventional imaging of diagnostic ultrasound is widely used. Although it makes the differences in the soft tissues echogenicities' apparent and clear, it fails in describing and estimating the soft tissue mechanical properties. It cannot portray their mechanical properties, such as the elasticity and stiffness.
arxiv
Strain stiffening universality in composite hydrogels and soft tissues [PDF]
arXiv, 2023 Soft biological tissues exhibit a remarkable resilience to large mechanical loads, a property which is associated with the strain stiffening capability of the biopolymer networks that structurally support the tissues. Yet, recent studies have shown that composite systems such as tissues and blood clots exhibit mechanical properties that contradict ...
arxiv
A Variational Beam Model for Failure of Cellular and Truss‐Based Architected Materials
Advanced Engineering Materials, EarlyView., 2023 Herein, a versatile and efficient beam modeling framework is developed to predict the nonlinear response and failure of cellular, truss‐based, and woven architected materials. It enables the exploration of their design space and the optimization of their mechanical behavior in the nonlinear regime. A variational formulation of a beam model is presented
Konstantinos Karapiperis +3 more
wiley +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source