Results 11 to 20 of about 724,859 (266)

Resection and reconstruction of huge tumors in the chest wall

Journal of Cardiothoracic Surgery, 2022
Objective To evaluate the experience and effects of resection and reconstruction of 4 cases of huge tumors in the chest wall. Methods The clinical data of 4 patients with huge tumors in the chest wall from July 2015 to January 2020 were collected and ...
Zhibing Dai, Maierdanjiang Maihemuti, Yachao Sun, Renbing Jiang   +3 more
doaj   +1 more source

FTY720 Attenuates LPS-Induced Inflammatory Bone Loss by Inhibiting Osteoclastogenesis via the NF-κB and HDAC4/ATF Pathways

Journal of Immunology Research, 2023
Osteoclast (OC) abnormalities lead to many osteolytic diseases, such as osteoporosis, inflammatory bone erosion, and tumor-induced osteolysis. Exploring effective strategies to remediate OCs dysregulation is essential.
Chongwei Chen, Sujing Zong, Zhenyu Wang, Ruijia Yang, Yanjing Guo, Yunfei Wang, Xinping Chen, Yue Li, Shaowei Wang   +8 more
doaj   +1 more source

Pelvic reconstruction following resection of tumour involving the whole ilium and acetabulum

Journal of Bone Oncology, 2019
Background: Functional reconstruction following resection of pelvic tumours with the ileum and the acetabulum involvement is challenging and demanding.
Huayi Qu, Dasen Li, Shun Tang, Jie Zang, Yifei Wang, Wei Guo   +5 more
doaj   +1 more source

Toxicity of zoledronic acid after intravenous administration: A retrospective study of 95 dogs

Journal of Veterinary Internal Medicine, 2022
Background There is a paucity of veterinary literature on the safety or outcome of zoledronic acid (ZA) use in dogs for either bone pain or hypercalcemia.
David John Brewer, Michael Macfarlane, Erin O'Connell, Nicholas J. Bacon   +3 more
doaj   +1 more source

INTRABEAM Intraoperative Radiation Therapy Combined with Limb Sparing Surgery in Soft Tissue Sarcoma (A Report of Four Cases)

Zhongliu Fangzhi Yanjiu, 2022
Objective To explore the clinical efficacy of surgical operation combined with INTRABEAM intraoperative radiotherapy in the limb-sparing treatment of soft tissue sarcoma.
WANG Yin, LI Bo, SONG Jianmin
doaj   +1 more source

Targeting TIMM23 to overcome osteosarcoma chemoresistance

Cell Death and Disease
Osteosarcoma (OS) is a malignant tumor whose chemoresistance severely compromises therapeutic efficacy. This study aims to investigate the molecular mechanism by which TIMM23 mediates M2 polarization of macrophages through mitophagy and regulates TIMM23 ...
Zhiwei Tao, Pingan Zou, Zhengxu Yang, Tao Xiong, Zhi Deng, Qinchan Chen   +5 more
doaj   +1 more source

Triamcinolone Acetonide affects TGF-β signaling regulation of fibrosis in idiopathic carpal tunnel syndrome

BMC Musculoskeletal Disorders, 2018
Background Fibroblast behavior and cell-matrix interactions of cells from normal and idiopathic carpal tunnel syndrome (CTS) subsynovial connective tissue (SSCT) with and without Triamcinolone Acetonide (TA) were compared in this study. A cell-seeded gel
Tai-Hua Yang, Anne Gingery, Andrew R. Thoreson, Dirk R. Larson, Chunfeng Zhao, Peter C. Amadio   +5 more
doaj   +1 more source

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia, Tarique Hussain, Jeanne Dillenbeck, Matthew Hammer, Annette von Drygalski, Guy Young, Ayesha Zia   +6 more
wiley   +1 more source

Single-cell multi-omics elucidates the role of RPS27-RPS24 fusion gene in osteosarcoma chemoresistance and metabolic regulation

Cell Death Discovery
Osteosarcoma (OS) presents significant treatment challenges due to chemoresistance. This study explores the molecular mechanisms underlying chemoresistance in OS, focusing on the novel fusion gene RPS27-RPS24. Using single-cell multi-omics techniques, we
Zhiwei Tao, Pingan Zou, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen   +5 more
doaj   +1 more source

Functional outcome of surgical treatment of adults with extremity osteosarcoma after megaprosthetic reconstruction—single-center experience

Journal of Orthopaedic Surgery and Research, 2019
Background Osteosarcoma is the most common primary malignant bone tumor in adults and is usually located in the long bones. Standard treatment consists of perioperative chemotherapy and radical surgical resection.
Tomasz Goryń, Andrzej Pieńkowski, Bartłomiej Szostakowski, Marcin Zdzienicki, Iwona Ługowska, Piotr Rutkowski   +5 more
doaj   +1 more source