Results 21 to 30 of about 826,793 (315)

Temporal effects of mechanical loading on deformation-induced damage in skeletal muscle tissue [PDF]

, 2010
Mechanical loading of soft tissues covering bony prominences can cause skeletal muscle damage, ultimately resulting in a severe pressure ulcer termed deep tissue injury.
S. Loerakker, Bader, D.L., Rijpkema, JJM Koo, K. Nicolay, Baaijens, F. P. T., C. W. J. Oomens, Strijkers, GJ Gustav, Oomens, CWJ Cees, Loerakker, S., Oomens, C.W.J., Nicolaij, K Klaas, Strijkers, G. J., Baaijens, FPT Frank, Rijpkema, J. J. M., Stekelenburg, A., G. J. Strijkers, Strijkers, G.j., Oomens, C. W. J., Loerakker, S Sandra, Stekelenburg, A Anke, D. L. Bader, Baaijens, F.P.T., Rijpkema, J.J.M., Bader, D. L., J. J. M. Rijpkema, F. P. T. Baaijens, Bader, DL Dan, A. Stekelenburg, Nicolay, K.   +28 more
core   +1 more source

Tissue-engineered collagenous fibrous cap models to systematically elucidate atherosclerotic plaque rupture [PDF]

, 2022
A significant amount of vascular thrombotic events are associated with rupture of the fibrous cap that overlie atherosclerotic plaques. Cap rupture is however difficult to predict due to the heterogenous composition of the plaque, unknown material ...
Wissing, T. B. (author), Smits, A. I.P.M., Serra, S. M., Serra, S.M., Wissing, T. B., Bouten, C.V.C., Van der Heiden, K., Gijsen, F.J.H. (author), Serra, S.M. (author), Smits, A.I.P.M.; id_orcid, Gijsen, F. J.H., Smits, A.I.P.M., Van der Heiden, K. (author), Bouten, C. V.C., Bouten, C.V.C.; id_orcid, Smits, A. I.P.M. (author), Wissing, T.B., Bouten, C. V.C. (author), Gijsen, F.J.H.   +18 more
core   +1 more source

Pelvic reconstruction following resection of tumour involving the whole ilium and acetabulum

Journal of Bone Oncology, 2019
Background: Functional reconstruction following resection of pelvic tumours with the ileum and the acetabulum involvement is challenging and demanding.
Huayi Qu, Dasen Li, Shun Tang, Jie Zang, Yifei Wang, Wei Guo   +5 more
doaj   +1 more source

Toxicity of zoledronic acid after intravenous administration: A retrospective study of 95 dogs

Journal of Veterinary Internal Medicine, 2022
Background There is a paucity of veterinary literature on the safety or outcome of zoledronic acid (ZA) use in dogs for either bone pain or hypercalcemia.
David John Brewer, Michael Macfarlane, Erin O'Connell, Nicholas J. Bacon   +3 more
doaj   +1 more source

INTRABEAM Intraoperative Radiation Therapy Combined with Limb Sparing Surgery in Soft Tissue Sarcoma (A Report of Four Cases)

Zhongliu Fangzhi Yanjiu, 2022
Objective To explore the clinical efficacy of surgical operation combined with INTRABEAM intraoperative radiotherapy in the limb-sparing treatment of soft tissue sarcoma.
WANG Yin, LI Bo, SONG Jianmin
doaj   +1 more source

Triamcinolone Acetonide affects TGF-β signaling regulation of fibrosis in idiopathic carpal tunnel syndrome

BMC Musculoskeletal Disorders, 2018
Background Fibroblast behavior and cell-matrix interactions of cells from normal and idiopathic carpal tunnel syndrome (CTS) subsynovial connective tissue (SSCT) with and without Triamcinolone Acetonide (TA) were compared in this study. A cell-seeded gel
Tai-Hua Yang, Anne Gingery, Andrew R. Thoreson, Dirk R. Larson, Chunfeng Zhao, Peter C. Amadio   +5 more
doaj   +1 more source

Single-cell multi-omics elucidates the role of RPS27-RPS24 fusion gene in osteosarcoma chemoresistance and metabolic regulation

Cell Death Discovery
Osteosarcoma (OS) presents significant treatment challenges due to chemoresistance. This study explores the molecular mechanisms underlying chemoresistance in OS, focusing on the novel fusion gene RPS27-RPS24. Using single-cell multi-omics techniques, we
Zhiwei Tao, Pingan Zou, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen   +5 more
doaj   +1 more source

CircDOCK1 promotes the tumorigenesis and cisplatin resistance of osteogenic sarcoma via the miR-339-3p/IGF1R axis

Molecular Cancer, 2021
Background Circular RNAs (circRNAs), a class of noncoding RNAs (ncRNAs), may modulate gene expression by binding to miRNAs. Additionally, recent studies show that circRNAs participate in some pathological processes.
Shenglong Li, Fei Liu, Ke Zheng, Wei Wang, Enduo Qiu, Yi Pei, Shuang Wang, Jiaming Zhang, Xiaojing Zhang   +8 more
doaj   +1 more source

Comprehensive transcriptomic analysis of immune-related eRNAs associated with prognosis and immune microenvironment in melanoma

Frontiers in Surgery, 2022
BackgroundRecent evidence suggests that enhancer RNAs (eRNAs) play key roles in cancers. Identification of immune-related eRNAs (ireRNAs) in melanoma can provide novel insights into the mechanisms underlying its genesis and progression, along with ...
Yuling Gan, Yuan Yang, Yajiao Wu, Tingdong Li, Libing Liu, Fudong Liang, Jianghua Qi, Peng Liang, Dongsheng Pan   +8 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source