Results 51 to 60 of about 1,281,265 (361)

The fusion gene LRP1–SNRNP25 drives invasion and migration by activating the pJNK/37LRP/MMP2 signaling pathway in osteosarcoma

Cell Death Discovery
Through transcriptome sequencing, we previously identified a new osteosarcoma-specific, frequent fusion gene, LRP1–SNRNP25, and found that it played an important role in tumor cell invasion and migration.
Peipei Xing, Haotian Liu, Wanyi Xiao, Gengpu Zhang, Chao Zhang, Zhichao Liao, Ting Li, Jilong Yang   +7 more
doaj   +1 more source

Albumin-bound paclitaxel and gemcitabine combination therapy in soft tissue sarcoma

BMC Cancer, 2020
Background The evidence that albumin-bound paclitaxel (nab-paclitaxel) is safe and efficacious for the treatment of many types of malignant tumors is continuously increasing.
Zhichao Tian, Fan Zhang, Po Li, Jiaqiang Wang, Jinpo Yang, Peng Zhang, Weitao Yao, Xin Wang   +7 more
doaj   +1 more source

Case report: Resection of a massive primary sacrococcygeal mature teratoma in an adult using 3-dimensional reconstruction and mixed reality technology

Frontiers in Surgery, 2022
IntroductionTeratomas are rare neoplasms that arise from pluripotent germ cells. Sacrococcygeal teratomas are often diagnosed in infants but are rare in adults; a mature teratoma can contain hair, teeth, bony tissue, and other mature tissue types. Herein,
He Zhang, Lu Ji, Jinxin Liu, Shizhe Li, Ting Chen, Jiatong Li, Guanning Shang   +6 more
doaj   +1 more source

Physiotherapists’ perceptions of problematic musculoskeletal soft tissue disorders [PDF]

, 2008
Original article can be found at: http://www.ijtr.co.uk/ Copyright MA Healthcare Limited.Aims: Many common musculoskeletal disorders are resistant to existing management strategies,causing long-term pain and disability.
Byrne, G., Poltawski, L., Watson, T.
core   +1 more source

A systematic review of criteria used to report complications in soft tissue and oncologic surgical clinical research studies in dogs and cats. [PDF]

, 2020
ObjectiveTo evaluate reporting of surgical complications and other adverse events in clinical research articles describing soft tissue and oncologic surgery in dogs and cats.Study designSystematic literature review.SampleEnglish-language articles ...
Balsa, Ingrid M, Culp, William TN, Follette, Christelle M, Giuffrida, Michelle A, Mayhew, Philipp D, Oblak, Michelle L, Singh, Ameet, Steffey, Michele A   +7 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Definitive Radiotherapy in the Management of Non-Resectable or Residual Retroperitoneal Sarcomas: Institutional Cohort Analysis and Systematic Review

Cancer Control, 2021
Background: There is currently no consensus on optimal management of patients with primary or recurrent non-resectable/residual retroperitoneal sarcomas (RPS). The objective of this study was to document the outcomes of patients with primary or recurrent
Aleksandra Sobiborowicz, Mateusz Jacek Spałek MD, PhD, Anna Małgorzata Czarnecka MD, PhD, MSc, Piotr Rutkowski MD, PhD   +3 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Long non-coding RNA AFAP1-AS1 accelerates the progression of melanoma by targeting miR-653-5p/RAI14 axis

BMC Cancer, 2020
Background Melanoma is the most aggressive skin cancer that derived from pigment cells, accounting for the majority of the skin-cancer-related deaths.
Fei Liu, Lanting Hu, Yi Pei, Ke Zheng, Wei Wang, Shenglong Li, Enduo Qiu, Guanning Shang, Jiaming Zhang, Xiaojing Zhang   +9 more
doaj   +1 more source

A Profile of Knee Injuries Suffered by Australian Army Reserve Soldiers [PDF]

, 2012
Despite having to perform the same occupational tasks as full-time soldiers, part-time soldiers may have lower levels of physical conditioning and report higher rates of injury per unit exposure to active service. The purpose of this study was to profile
Dey, Paramita, Mukhopadhyaya, Biswarup, Roy, Sourov, Vempati, Sudhir K.   +3 more
core   +2 more sources