Results 71 to 80 of about 826,793 (315)

MTHFD1L is a novel prognostic marker and therapeutic target in cutaneous melanoma

Diagnostic Pathology
Background Skin cutaneous melanoma (SKCM) is one of the highly malignant tumor. This study aimed to investigate the expression levels of MTHFD1L in cutaneous melanoma and to uncover its potential biological significance.
Xinlian Xie, Guangfu Shi, Kebin Ning, Zhenjie Wu   +3 more
doaj   +1 more source

Soft Tissue Reconstruction and Integration to Implant After Bone-Tumor Resection: A Current Concept Review

Introduction: With the advancements in chemotherapy for malignant bone tumors, the number of patients eligible for limb salvage surgery has increased. Surgeons face a subsequent challenge in limb-sparing resection due to the need for reconstructing soft ...
Raffaele Vitiello, Tommaso Greco, Giulio Maccauro, Antonio Ziranu, Elisa Pesare, Giuseppe Solarino   +5 more
core   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

Advanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir, Jixing Lin, Yuncang Li, Li Zhu, Paul F. A. Wright, Cuie Wen   +5 more
wiley   +1 more source

BRAF mutation and its inhibitors in sarcoma treatment

Cancer Medicine, 2020
The mitogen‐activated protein kinase (MAPK) signaling pathway plays a significant role in mediating cellular physiological activities, such as proliferation, differentiation, apoptosis, and senescence.
Haotian Liu, Nahar Nazmun, Shafat Hassan, Xinyue Liu, Jilong Yang   +4 more
doaj   +1 more source

Myoepithelioma of soft tissue

Indian Journal of Pathology and Microbiology, 2009
Myoepitheliomas and mixed tumors involving deep subcutaneous and subfascial soft tissues of limb or limb girdle are rare lesions as against salivary lesions that are well established conditions. Here, we report a 22-year-old female who presented with painful hard swelling in the left gluteal region of 1(1/2) year duration.
Pai Mukhta, Naik Ramadas, Kamath Ramachandra, Magar Dilasma   +3 more
openaire   +3 more sources

Experimental Safety Study on Soft-tissue Injury in Robotics

, 2011
This article details the analysis of soft-tissue injuries caused by sharp tools that are mounted on/grasped by a robot. The evaluation is considered as the next step down the road to a complete safety analysis of robots for humanâ  robot interaction ...
Hirzinger, Gerd, Albu-Schäffer, Alin Olimpiu, Haddadin, Fahed, Roßmann, Jürgen, Haddadin, Sami   +4 more
core  

A physically motivated constitutive model for cell-mediated compaction and collagen remodeling in soft tissues

, 2014
Collagen is the main load-bearing component of many soft tissues and has a large influence on the mechanical behavior of tissues when exposed to mechanical loading.
Baaijens, FPT Frank, Obbink-Huizer, C Christine, Loerakker, S Sandra, Loerakker, S., Obbink - Huizer, C., Baaijens, F.P.T.   +5 more
core   +1 more source

Efficacy of consolidation high-dose chemotherapy with ifosfamide, carboplatin and etoposide (HD-ICE) followed by autologous peripheral blood stem cell rescue in chemosensitive patients with metastatic soft tissue sarcomas [PDF]

, 2006
Background: Prognosis of patients with metastatic soft tissue sarcomas (MSTS) is poor even after response to doxorubicin-based chemotherapy. We report phase II data of highdose chemotherapy and peripheral blood stem cell (PBSC) rescue in patients with ...
Hentrich, M., Licht, Thomas, Straka, Christian, Rolf-Dieter Issels, Wendtner, Clemens-Martin, Marcus Schlemmer, Hiddemann, Wolfgang, Abdel-Rahman, Sultan, Sultan Abdel-Rahman, Issels, Rolf-Dieter, Salat, C., Baumert, Jens, Straka, C., Hiddemann, W., Falk, Martin, Issels, R.D., Wolfgang Hiddemann, Martin Falk, Jens Baumert, Falk, M., Thomas Licht, Schlemmer, M., Marcus Hentrich, Licht, T., Salat, Christoph, Christoph Salat, Abdel-Rahman, S., Clemens-Martin Wendtner, Schlemmer, Marcus, Wendtner, C.M., Baumert, J.J., Hentrich, Marcus, Christian Straka   +32 more
core   +1 more source

Natural Bone‐Derived Ceramic Scaffolds Functionalized with Chitosan‐Gold, Chitosan‐Magnesium, and Chitosan‐Zinc for Enhanced Antibacterial Activity

Advanced Engineering Materials, EarlyView.
This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian, Anh Thi Le, Anh Thi Van Le, Dung My Thi Dang, Tin Chanh Duc Doan, Chien Mau Dang, Martin Bolduc   +6 more
wiley   +1 more source