Results 51 to 60 of about 1,428,378 (361)

Soft tissue sarcomas

open access: yesEuropean Journal of Cancer, 1997
The soft tissue sarcomas (STS) constitute approximately 15% of all canine and 7% of all feline skin and subcutaneous tumors. STS are tumors that arise from a variety of mesenchymal tissues. The aggressive nature of STS in cats, especially those tumors occurring after vaccination, suggests that novel therapies should be investigated.
openaire   +4 more sources

Identification and characterization of mitochondrial autophagy-related genes in osteosarcoma and predicting clinical prognosis

open access: yesScientific Reports
Osteosarcoma (OS), the most prevalent primary malignant bone tumor, is characterized by a poor prognosis and high metastatic potential. Mitochondrial autophagy has been implicated in cancer suppression.
Hongliang Zhang   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Formation of the sacrum requires down-regulation of sonic hedgehog signaling in the sacral intervertebral discs

open access: yesBiology Open, 2018
In humans, the sacrum forms an important component of the pelvic arch, and it transfers the weight of the body to the lower limbs. The sacrum is formed by collapse of the intervertebral discs (IVDs) between the five sacral vertebrae during childhood, and
Raffaella Bonavita   +3 more
doaj   +1 more source

LncRNA PCBP1-AS1-mediated AR/AR-V7 deubiquitination enhances prostate cancer enzalutamide resistance

open access: yesCell Death and Disease, 2021
The refractory of castration-resistant prostate cancer (CRPC) is mainly reflected in drug resistance. The current research on the resistance mechanism of CRPC is still in its infancy.
Boya Zhang   +6 more
doaj   +1 more source

Presumed choroidal metastasis from soft tissue myoepithelial carcinoma [PDF]

open access: yes, 2019
Purpose: To report a case of presumed choroidal metastasis from soft tissue myoepithelial carcinoma and highlight challenges in its diagnosis. Observations: A 52-year-old man was referred with a two-week history of photopsia in his left eye.
Bonar, Fiona   +4 more
core   +1 more source

Impending Total Airway Collapse Involving a Maxillary Removable Partial Denture: A Clinical Report [PDF]

open access: yes, 2018
This article presents a rare incident of a bilateral maxillary removable partial denture as an airway foreign body. The removable partial denture and the surrounding soft tissue irritation caused partial obstruction of the airway.
Maroulakos, Georgios   +1 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Phase II trial of VEGFR2 inhibitor apatinib for metastatic sarcoma: focus on efficacy and safety

open access: yesExperimental and Molecular Medicine, 2019
Cancer: Starving sarcomas into submission A drug that inhibits blood vessel growth offers a potentially promising treatment for a class of tumors with a poor prognosis.
Zhichao Liao   +17 more
doaj   +1 more source

Soft tissue injections [PDF]

open access: yesBest Practice & Research Clinical Rheumatology, 2005
Soft tissue rheumatism includes a wide spectrum of common lesions of the tendons, enthesis, tendon sheaths, bursae, ligaments and fasciae as well as nerve compression syndromes. Studies on the pathogenesis of these lesions do not support a major role for inflammation, thus questioning the rationale for glucocorticoid injections.
Inês, Luís P. B. S.   +1 more
openaire   +3 more sources

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