Results 91 to 100 of about 724,859 (266)

Mitochondria dysfunction and increased expression of WNT5A and BNIP3 in tenocytes obtained from patients with tendinopathy

JSES International
: Background: Tendinopathy is a significant source of pain and functional impairment, with contributions from various extrinsic and intrinsic factors.
Yusuke Nakagawa, MD, PhD, Yuki Okazaki, MD, PhD, Camila B. Carballo, PT, PhD, Susumu Wada, MD, PhD, Daniel Nemirov, MD, Elizabeth R. Selvaggio, MD, Amir H. Lebaschi, MD, Xiang-Hua Deng, MD, Miguel Otero, PhD, Michelle L. Delco, DVM, PhD, Lisa A. Fortier, DVM, PhD, Scott A. Rodeo, MD   +11 more
doaj   +1 more source

Implantable Ionic Memristors Based on Natural Polymer Heterojunctions

Advanced Functional Materials, EarlyView.
We report an implantable natural polymer‐based ionic memristor composed of hyaluronic acid, chitosan, and PDMS. The device achieved 98.94% accuracy in MNIST classification while reducing training time by 36.8% compared with a conventional artificial neural network (ANN).
Dong‐yup Lee, Byung Ik Park, Gihyeon Yim, Hyunjae Yoo, Sangjun Ma, Jundong Park, Jeong‐Yun Sun   +6 more
wiley   +1 more source

Versatile Pneumatic Twisted Coiled Actuators Enabled by Fiber‐Polymer Composite Fabrication

Advanced Functional Materials, EarlyView.
This work reports composite Pneumatic Twisted Coiled Actuators with embedded Kevlar fibers that convert pneumatic or hydraulic pressure into powerful linear motion. A novel precise manufacturing technique is used to systematically explore how design variables influence actuator mechanics and dynamics.
William J. Townsend, Jeongmin Kim, Samuel Tsai, Yichao Shi, Sameh Tawfick, James H. Pikul   +5 more
wiley   +1 more source

Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway

Molecular Medicine
Background Soy isoflavones (SI) is a natural bioactive substance exhibiting beneficial effects on human health. This study aims to elucidate the therapeutic potential of SI in the treatment of osteosarcoma (OS) and to investigate the underlying ...
Ziang Zheng, Xinghan Zhao, Bo Yuan, Shan Jiang, Rushan Yan, Xiaowei Dong, Qijun Yao, Haidong Liang   +7 more
doaj   +1 more source

Sarcomas of the Soft Tissues [PDF]

CA: A Cancer Journal for Clinicians, 1961
openaire   +2 more sources

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

From Geometry to Function: Programmable Mechanical Response in 3D‐Printed Adipose‐Inspired Soft Metamaterials

Advanced Functional Materials, EarlyView.
Geometry‐driven design of soft cellular metamaterials is systematically investigated by combining experiments, finite element modeling, and statistical prediction. The study quantifies how unit cell geometry and material properties govern stiffness, instability, densification, and energy absorption.
Alice Berardo, Gianmarco Dolino, Damiano Coato, Paolo Gargiulo, Emanuele Luigi Carniel   +4 more
wiley   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

Advanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han, Shuvra Mondal, Sungkeun Han, Chan‐Hwi Eom, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +5 more
wiley   +1 more source

Tissue‐Adhesive Fabric‐Based Bioelectronics for Wearable and Implantable Applications

Advanced Functional Materials, EarlyView.
An implantable and wearable bioelectronic textile (iTextile) is introduced as a unified platform bridging wearable and implantable systems. By integrating a self‐healing polymer, stretchable silk fabric, conductive composite electrodes, and an adhesive hydrogel, the platform enables conformal, stable interfacing with soft tissues. The iTextile supports
Soojung An, Yewon Kim, Kyoungryong Kim, Heewon Choi, Sungjun Yoon, Jaewon Ju, Mikyung Shin, Donghee Son   +7 more
wiley   +1 more source