Results 101 to 110 of about 826,793 (315)

Multimodal Soft Surgical Robots Enabled by Eco‐Degradable, Sterilizable Polymers and Transient Electronics

Advanced Functional Materials, EarlyView.
A compostable PGS soft surgical robot with interchangeable modules integrates transient Mo tactile and Si thermal sensors for dual feedback. The device preserves its function after clinical‐grade sterilization, demonstrates stable actuation and cardiac tissue grasping with real‐time in vivo pulsatile monitoring, and biodegrades post‐use with soil‐safe, 
Minseong Chae, Kyung‐Sub Kim, Gyeong‐Seok Hwang, Jun‐Seok Shim, Sung‐Woo Kim, Yong‐Wu Kim, Jieun Han, Jae‐Young Bae, Jae‐Hwan Lee, Minjung Chae, Jooik Jeon, Joo‐Hyeon Park, You‐Jung Park, Ju‐Yong Lee, Sung‐Geun Choi, Min‐Ha Oh, Yong‐Joong Shin, Young‐In Ryu, Ji‐Woo Gu, Seong‐Yu Choi, Jeong‐Yun Sun, Jung Keun Hyun, Myoung‐Ryul Ok, Sang Yup Kim, Edyta Wyszkowska, Ju‐Young Kim, Kang‐Sik Lee, Seung‐Kyun Kang   +27 more
wiley   +1 more source

Tebentafusp (IMCgp100) in the treatment of uveal melanoma — from preclinical evidence to clinical practice

Nowotwory
Tebentafusp (IMCgp100) is a novel bispecific immunotherapy that contains a specifically engineered soluble T-cellreceptor (TCR) capable of recognising the gp100 epitope on the surface of tumour cells presented by human leukocyteantigen-A*02:01 (HLA- A*02:
Piotr Remiszewski, Eryk Siedlecki, Julia Wąż, Kinga Filipek, Agata Pisklak, Wiktor Gaik, Monika Dudzisz-Śledź, Piotr Rutkowski, Anna M. Czarnecka   +8 more
doaj   +1 more source

Low oxygen concentrations impair tissue development in tissue-engineered cardiovascular constructs

, 2012
Cardiovascular tissue engineering has shown considerable progress, but in vitro tissue conditioning to stimulate the development of a functional extracellular matrix still needs improvement.
Baaijens, FPT Frank, Vlimmeren, M.A.A. van, Stoop, R, Broek, van den, W.J.T., Driessen - Mol, A., Bouten, C.V.C., Bouten, CVC Carlijn, Stoop, R., Baaijens, F.P.T., Vlimmeren, van, M.A.A., Driessen-Mol, A Anita, Oomens, CWJ Cees, Bouten, C.V.C.; id_orcid, Broek, M. van den, Driessen-Mol, A., Oomens, C.W.J., Vlimmeren, MAA Marijke van, Broek, WJT van den   +17 more
core   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

Advanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam, Seon Yeong Chae, Young Woo Kwon, Hye Jin Heo, Hye Rin Lee, Ji Hyeok Lee, Dong‐Wook Han, Yun Hak Kim, Suck Won Hong   +8 more
wiley   +1 more source

The effect of continuous long-term illumination with visible light in different spectral ranges on mammalian cells

Scientific Reports
One of the biggest challenges in tissue engineering and regenerative medicine is to ensure oxygen supply of cells in the (temporary) absence of vasculature. With the vision to exploit photosynthetic oxygen production by microalgae, co-cultivated in close
Finn Dani, Kathleen Schütz, Ezgi Dikici, Anne Bernhardt, Anja Lode   +4 more
doaj   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Non-invasive techniques for predicting soft tissue during pressure induced ishaemia.

, 1997
PhDSoft tissue breakdown occurs in association with biochemical changes that can be attributed to a reduction in blood and lymph flow to a localised tissue area in response to applied pressure.
Knight, Sarah Louise
core  

The importance of internal strain as opposed to interface pressure in the prevention of pressure related deep tissue injury

, 2010
For pressure ulcer prevention an ambitious goal would be the establishment of a mechanical threshold for tissue damage. In the past, several researchers have sought to establish such a threshold often involving the loading time.
Oomens, CWJ Cees, Bader, D.L., Loerakker, S Sandra, Loerakker, S., Oomens, C.W.J., Bader, DL Dan, Loerakker, Sandra   +6 more
core   +1 more source

Investigating the influence of intermittent and continuous mechanical loading on skin through non-invasive sampling of IL-1α [PDF]

, 2019
\u3cp\u3ePressure ulcers (PUs) are a major burden to both patients, carers and the healthcare system. It is therefore important to identify patients at risk and detect pressure ulcers at an early stage of their development.
Worsley, P R, Oomens, CWJ Cees, Bader, D.L., Soetens, JFJ Jibbe, Bader, DL Dan, Soetens, J.F.J., Oomens, C.W.J., Worsley, P.R.   +7 more
core   +1 more source

Texoskeletons: Developing the Fundamental Technologies for Creating Intelligent Soft Robotic Clothing With Integrated 1D Sensors and Actuators

Advanced Functional Materials, EarlyView.
ABSTRACT Traditional wearable exoskeletons rely on rigid structures, which limit comfort, flexibility, and everyday usability. This work introduces the fundamental technologies to create the first soft, lightweight, intelligent textile‐based exoskeletons (Texoskeletons) built using 1D sensors and actuators.
Amy Lukomiak, Rameesh Bulathsinghala, Jack Varga, Shuxin Meng, Kalana Marasinghe, Imaad Refai, Biyon Fernando, Amitkumar Patel, Chamika M. Halloluwa‐Arachchige, Carlos Oliveira, Arash M. Shahidi, Zahra Rahemtulla, Alexander Turner, Ziyun Ding, Bernard X. W. Liew, Andy Kerr, Ezio Preatoni, Theo Hughes‐Riley, Ishara Dharmasena, Pasindu Lugoda   +19 more
wiley   +1 more source