CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]
, 2016 Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien +12 more
core +2 more sources
Fine needle aspiration for the diagnosis and treatment of musculoskleletal tumours
Acta Orthopaedica et Traumatologica Turcica, 2017 Objective: The aim of this study was to evaluate the diagnostic accuracy of FNA and analyse its efficacy in enabling the initiation of treatment in musculoskeletal tumours.
Pedro Cardoso +4 more
doaj +1 more source
Biphenotypic Sinonasal Sarcoma-Case Report and Review of Clinicopathological Features and Diagnostic Modalities. [PDF]
, 2019 Background Biphenotypic sinonasal sarcoma is a recently described malignancy showing dual differentiation with both myogenic and neural elements. Due to its histologic similarities to other sinonasal malignancies, it is a diagnostic challenge.
Chitguppi, Chandala +6 more
core +2 more sources
Spindle Cell Tumours of the Head and Neck-A Taxonomic Review [PDF]
Journal of Clinical and Diagnostic Research, 2018 Spindle cell neoplasms of the head and neck region are relatively rare, yet there importance cannot be doubted. Spindle cells are of mesenchymal origin and constitute a part of the body’s connective tissue.
Esha Singh
doaj +1 more source
Commentary on "a case of paratesticular leiomyosarcoma successfully treated with orchiectomy and chemotherapy" [PDF]
, 2015 We have read with great interest the article written by Ko and colleagues on a particularly rare type of malignant mesenchymal tumor that is paratesticular leiomyosarcoma and we did appreciate the argumentation on the utility of adjuvant chemotherapy as ...
Marchetti, Paolo +3 more
core +1 more source
Soft Tissue Special Issue: Chondroid Neoplasms of the Skull [PDF]
Head and Neck Pathology, 2020 Clinically, radiologically, and pathologically, chondroid neoplasms of the skull can be diagnostically challenging due to overlapping features in each of these domains. Compounding the problem for the pathologist, there is also significant morphologic, immunophenotypic, and molecular genetic overlap between benign and malignant cartilaginous lesions ...
A. N. Flaman +3 more
openaire +3 more sources
Odontogenic Myxoma Of The Maxilla: A Clinical Case Report And Review Of Literature [PDF]
, 2013 Odontogenic myxomas are rare benign mesenchymal tumours of head and neck with a potential for local infiltration and recurrence. They appear to originate from the dental papilla, follicle or periodontal ligament in mandible and less commonly the ...
Bhardwaj, Vikram +3 more
core +2 more sources
Molecular targeted therapy for advanced or metastatic soft tissue sarcoma
Cancer Control, 2021 Soft tissue sarcomas are a form of rare and heterogeneous neoplasms with high recurrence rate and mortality. Over the past decades, less progress has been achieved.
Jin Yuan MD +2 more
doaj +1 more source
Glomangiomyoma of the knee : a rare juxtasynovial presentation [PDF]
, 2020 Glomus tumors are benign tumors typically located in the subcutis or deep dermis of the subungual region of the fingers. Histologically, glomus tumors are divided into three subtypes, in descending order of frequency: solid glomus tumor, glomangioma and ...
De Backer, Adelard +2 more
core +1 more source
Circumferential ankle leiomyoma with intratendinous involvement: A case report
Foot & Ankle Surgery: Techniques, Reports & CasesLeiomyomas are mostly benign soft tissue neoplasms arising from smooth muscle. These neoplasms are infrequent in the lower extremity accounting for about 1.7 % of all benign soft tissue tumors.
Lauren Simon, DPM +2 more
doaj +1 more source