Results 91 to 100 of about 710,485 (229)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Sourcing Lifecycle for Software as a Service (SAAS)
EPJ Web of Conferences, 2014 In recent years, Software as a Service (SaaS) has changed from curiosity caused concept to an accepted well known concept. A key advantage of this model is that, by cautious engineering, it is possible to influence economy of scale to decrease total cost
Santy , Sikkel K.
doaj +1 more source
Using Technology Enabled Qualitative Research to Develop Products for the Social Good, An Overview [PDF]
, 2010 This paper discusses the potential benefits of the convergence of three recent trends for the design of socially beneficial products and services: the increasing application of qualitative research techniques in a wide range of disciplines, the rapid ...
Burkhard, R., Roldan, Maria Malu H.
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Free and open source cloud technology based on the type Software as a Service
CTE Workshop Proceedings, 2017 The aim of this study is to design and implement the cloud computing technology with types of the services Software as a Service (SaaS). Objectives of the study is to analyze the free and open source cloud technology based on the type Software as a ...
Nataliya Mihailivna Kiyanovska
doaj +1 more source
, 2015 Modelling & Simulation (M&S) is broadly used in real scenarios where making physical modifications could be highly expensive. With the so-called Simulation Software-as-a-Service (SimSaaS), researchers could take advantage of the huge amount of resource ...
Azevedo, Tiago +2 more
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
To Share or Not to Share in Client-Side Encrypted Clouds
, 2014 With the advent of cloud computing, a number of cloud providers have arisen to provide Storage-as-a-Service (SaaS) offerings to both regular consumers and business organizations.
Ateniese, Giuseppe, Wilson, Duane
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