Results 61 to 70 of about 2,114,299 (265)

MHSDN: A Hierarchical Software Defined Network Reliability Framework design

IET Information Security, 2023
At present, attacks based on the vulnerability of the controller and flooding attacks still constitute a principal threat for hierarchical Software Defined Network (SDN), such as flow table tampering, malicious Application attacks, Distributed Denial of ...
Zhengbin Zhu, Qinrang Liu, Dongpei Liu, ChenYang Ge, Chong Wang   +4 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Multi-controller Load Balancing Architecture Based on Software Defined Network [PDF]

Jisuanji gongcheng, 2016
Through the analysis of multiple of distributed architectures of Software Defined Network(SDN),a new architecture named the Distributed Control Architecture(DCA) is proposed based on SDN.DCA separates the control layer into load balancing layer and ...
ZHANG Minmin,ZHANG Yun,DUAN Yuanxin
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The Influence of Failover on Software-Defined Network and Conventional Network

Journal of Internet and Software Engineering, 2020
The growing use of the Internet resulted in the number of agencies that use two or more internet gateway paths or so-called Internet Service Providers (ISPs) to maintain network availability. Using two or more gateway paths allows break-up of connections
Riffat Hasan Saputra, Alif Subardono
doaj   +1 more source

Joint Congestion Control Strategy in Software Defined Content Network [PDF]

Jisuanji gongcheng, 2016
Content-centric Network(CCN) provides a solution to solve the problem of content acquisition and distribution in the view of network architecture.The finiteness of network resource and unexpectedness of network traffic result in network congestion ...
ZHANG Yuncan,WANG Lei,LIU Jing,WANG Song
doaj   +1 more source

An Empirical Model of Packet Processing Delay of the Open vSwitch

, 2017
Network virtualization offers flexibility by decoupling virtual network from the underlying physical network. Software-Defined Network (SDN) could utilize the virtual network.
Matrawy, Ashraf, Sattar, Danish
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

SDN Access Control for the Masses

, 2018
The evolution of Software-Defined Networking (SDN) has so far been predominantly geared towards defining and refining the abstractions on the forwarding and control planes. However, despite a maturing south-bound interface and a range of proposed network
Gehrmann, Christian, Paladi, Nicolae
core   +1 more source