Results 121 to 130 of about 54,945 (291)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

An intelligent zero trust secure framework for software defined networking. [PDF]

PeerJ Comput Sci, 2023
Guo X, Xian H, Feng T, Jiang Y, Zhang D, Fang J.   +5 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Software-Defined Named Data Networking in Literature: A Review

Future Internet
This paper presents an in-depth review of software-defined named data networking (SD-NDN), a transformative approach in network architectures poised to deliver substantial benefits.
Albatool Alhawas, Abdelfettah Belghith
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Dynamic reconfiguration technologies based on FPGA in software defined radio system

, 2011
Partial Reconfiguration (PR) is a method for Field Programmable Gate Array (FPGA) designs which allows multiple applications to time-share a portion of an FPGA while the rest of the device continues to operate unaffected.
Crockett, Louise Helen, He, Ke, Stewart, Robert   +2 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Software-Defined Networking powered by AI-driven Anomaly Detection

Journal of Cybersecurity Education, Research & Practice
Software Defined Networking (SDN) revolutionizes network control by separating the control plane from the data plane. Although the latter improves SDN agility and scalability, it creates a security hole, particularly in a central control plane, leading ...
Dina Moloja, Vusumuzi Malele
doaj   +1 more source

DoSDefender: A Kernel-Mode TCP DoS Prevention in Software-Defined Networking. [PDF]

Sensors (Basel), 2023
Wang D, Zhao Y, Zhi H, Wu D, Zhuo W, Lu Y, Zhang X.   +6 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source