Results 121 to 130 of about 15,524,849 (357)

Towards Coordination-Intensive Visualization Software [PDF]

open access: yes, 2003
Most coordination realizations in current visualization systems are ''last-minute'' ad-hoc and rely on the richness of the chosen implementation language. Moreover, very few visualization models implicitly consider coordination.
Boukhelifa, Nadia   +2 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Software Builders

open access: yesIEEE Software, 2008
The tools and processes we use to transform our system's source code into an application that we can deploy or ship have always been important, but nowadays they can mean the difference between success and failure. The reasons are simple: larger code bodies; teams that are bigger, more fluid, and more widely distributed; richer interactions with other ...
openaire   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Characterization of security defects and analysis of vulnerability criticality in software for automated systems of internal affairs bodies

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. The purpose of the study is to theoretically analyze security defects and study the criticality of vulnerabilities in software used in modern automated systems of internal affairs agencies.Method.
I. G. Drovnikova, A. D. Popova
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Heron, a Knowledge Graph editor for intuitive implementation of Python-based experimental pipelines

open access: yeseLife
To realise a research project, experimenters face conflicting design and implementation choices across hardware and software. These include balancing ease of implementation – time, expertise, and resources – against future flexibility, the number of ...
George Dimitriadis   +3 more
doaj   +1 more source

On Software Implementation of Gabidulin Decoders [PDF]

open access: green, 2020
Johannes Kunz   +4 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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