Results 151 to 160 of about 14,659,030 (367)
Journal of Educational, Cultural and Psychological Studies, 2010 «Fenix»: A Preschool and Primary School Project to Fight the Effects of Socio-Cultural Deprivation Many studies have shown the spreading of serious learning difficulties in socio-culturally disadvantaged children and the effects of those on their ...
Cristina Coggi, Paola Ricchiardi
doaj
The Evaluation of E-learning Design in Female High School Students of Arak District 2 From Point of View of Teachers, Administrators and Students and Possible Optimizing Strategies [PDF]
Interdisciplinary Journal of Virtual Learning in Medical Sciences, 2013 Introduction: This study aims at evaluating the e-learning in female secondary schools of Arak district two. Materials & Methods: The required number of the sample was calculated using the Morgan's table, which was 217 for students, 7 for school ...
Maryam Sharifi, Alireza Faghihi
doaj
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Desafíos y estrategias prácticas de los estudios empíricos sobre las técnicas de prueba del software
, 1969 Édgar Serna M., Fernando Arango
openalex +2 more sources
UNIX TM as an environment for producing numerical software [PDF]
, 1978 N. L. Schryer
openalex +1 more source
Software Deposit: Where To Deposit Software
, 2018 This work was funded by Jisc. The Software Sustainability Institute is supported by EPSRC grant EP/H043160/1 and EPSRC/BBSRC and ESRC grant EP/N006410/1.
openaire +3 more sources
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source