Results 201 to 210 of about 1,521,635 (308)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Toward Cybersecurity Testing and Monitoring of IoT Ecosystems. [PDF]

SN Comput Sci
Taylor S, Jaatun MG, Omerovic A, Borgaonkar R, Seidl R, Goetze N, Kuhr J, Prosvirin D, Leone M, Kuznetsov A, Gritskevich A, Mpantis A, Perales OG, Wenning BL, Duttagupta S.   +14 more
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

A rare collision tumor of lymphoepithelioma-like carcinoma and t-cell lymphoma: a case report. [PDF]

Front Oncol
Zhu M, Zhang J.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Habitat-Based Radiomics for Predicting Visceral Pleural Invasion in Subpleural Nodules with Solid Component on Low-Dose CT: A Multicenter Study. [PDF]

Diagnostics (Basel)
Long Y, Li X, Li Y, Zheng Y, Lin W, Zhou P, Liu J.   +6 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

PASTA-4-PHT: a pipeline for automated security and technical audits for the personal health train. [PDF]

BMC Med Inform Decis Mak
Welten S, Kindermann K, Polat A, Görz M, Jugl M, Neumann L, Neumann A, Lohmöller J, Pennekamp J, Decker S.   +9 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Mixed endometrial carcinoma: is it time to profile the two components separately? [PDF]

Front Oncol
Musettini G, Pretelli P, Giusti A, Cupini S, Coltelli L, De Luca F, De Maio E, Finale C, Masini LC, Soria G, Cirigliano G, Viacava P, Donati S, Valsuani C, Caparello C, Lucchesi M, Furfaro I, Antonelli A, Abate S, Bracco GL, Marrai R, Liut M, Masoni S, Pini C, Mignogna M, Cocuzza P, Ginori A, Vivaldi F, Acconci G, Arrighi G, Barletta MT, Barbara C, Stasi I, Farnesi A, Marini A, Pellino A, Sammarco E, Rosada J, Orlandi F, Cavazzana A, Allegrini G.   +40 more
europepmc   +1 more source