Results 61 to 70 of about 1,676,132 (304)
A Universal Integration Framework for Web-Based Learning Tools: Enabling Seamless Interoperability
Open Education StudiesThe integration of diverse and heterogeneous learning technologies into cohesive educational platforms presents significant challenges, particularly in enabling real-time communication, personalization, and adaptability.
Karkalas Sokratis
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Assessing the Real Impact of Open-Source Components in Software Systems
IEEE Access, 2023 Open-source libraries form the backbone of modern software systems, making software composition analysis (SCA) a vital part of the software development cycle. Despite its importance, current SCA methods, primarily focusing on open-source component issues,
Andy Molin +2 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Software Component Certification: A Component Quality Model
Anais do V Simpósio Brasileiro de Qualidade de Software (SBQS 2006), 2006 Component-based software development is becoming more generalized, representing a considerable market for the software industry. However, several technical issues remain unsolved before the software components industry reaches the maturity as other software industries.
Alexandre Alvaro +1 more
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Organising the knowledge space for software components [PDF]
, 2005 Software development has become a distributed, collaborative process based on the assembly of off-the-shelf and purpose-built components. The selection of software components from component repositories and the development of components for these ...
Pahl, Claus
core
Educational Technologies Based on Software Components [PDF]
Informatică economică, 2006 Informatics technologies allow to easily develop and adapt e-learning systems. In order to be used by any users, the system must be developed to permit the lessons construction in a dynamic way.
Marian DARDALA +2 more
doaj
The Quantitative Measurement of Software Components Reusability: Methods, Applications, Challenges [PDF]
مجله مدل سازی در مهندسی, 2016 The main goal of reusing software components is to produce new software systems using existing components rather than building it from scratch. Component-based software development is one of the most common approaches found today in different branches of
Bahareh Bafandeh, Abbas Rasoolzadegan
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