Results 71 to 80 of about 1,676,132 (304)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Energy efficiency on the product roadmap: an empirical study across releases of a software product [PDF]
, 2017 In the quest for energy efficient Information and Communication Technology, research has mostly focused on the role of hardware. However, the impact of software on energy consumption has been acknowledged as significant by researchers in software ...
Jan Martijn van der Werf +20 more
core +1 more source
Open-source GIS software and components for modelling watershed phenomena
GEOmedia, 2022 The Soil and Water Assessment Tool (SWAT) enables the simulation of watershed and river basin quantity and quality of surface and ground water under the influence of land use, management, and climate change.
Flavio Lupia, Giuseppe Pulighe
doaj +4 more sources
DETECTING BINARY INCOMPATIBLE SOFTWARE COMPONENTS USING DYNAMIC LOADER
Studia Universitatis Babes-Bolyai: Series Informatica, 2018 Modern programming languages support modular development dividing the system into separate translation units and compile them individually. A linker is used then to assemble together these units either statically or dynamically.
Áron BARÁTH, Zoltán PORKOLÁB
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A software for Estimating Biodiversity Components (BİÇEB)
Turkish Journal of Forestry, 2020 Biodiversity is of crucial importance for ecosystem health and functioning. It is thus one of the most important topics in the various disiplines of the Naturel Science. Various indices have been improved to measure biodiversity.
Kürşad Özkan +5 more
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Learning to select software components
, 2004 Developers using software components need to be confident in their selection of the most suitable component. Manual searching is time consuming and unlikely to be able to consider large numbers of components. The Context-driven Component Evaluation (CdCE)
Maxville, V., Lam, C.P., Armarego, J.
core