Results 111 to 120 of about 7,286,866 (372)

The TASTE Toolset: turning human designed heterogeneous systems into computer built homogeneous software. [PDF]

open access: yes, 2010
The TASTE tool-set results from spin-off studies of the ASSERT project, which started in 2004 with the objective to propose innovative and pragmatic solutions to develop real-time software. One of the primary targets was satellite flight software, but it
Conquet, Eric   +4 more
core  

A Taxonomy for a Constructive Approach to Software Evolution

open access: yesJournal of Software, 2007
In many software design and evaluation techniques, either the software evolution problem is not systematically elaborated, or only the impact of evolution is considered. Thus, most of the time software is changed by editing the components of the software system, i.e. breaking down the software system.
Mehmet Aksit   +2 more
openaire   +3 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

An improved resource allocation method for mapping service function chains based on A3C

open access: yesIET Communications
Network function virtualization (NFV) technology deploys network functions as software functions on a generalised hardware platform and provides customised network services in the form of service function chain (SFC), which improves the flexibility and ...
Wanwei Huang   +5 more
doaj   +1 more source

Application of JKSimBlast software in drifting operations [PDF]

open access: yesPodzemni Radovi, 2019
This paper presents a review of the advantages of application of JKSimBlast 2DFace software in design phase of underground premises. The aim of this research was to show possibilities of the software and possibility of its application in design of ...
Crnogorac Luka   +4 more
doaj  

4D Applications of GIS in Construction Management

open access: yesAdvances in Civil Engineering, 2017
Construction industries broadly involve different set of construction activities which are to be executed as per schedule and the major software used for scheduling is PRIMAVERA and Microsoft Project (MSP).
A. Chaitanya Kumar, T. Reshma
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

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