Results 111 to 120 of about 6,621,117 (310)
E3S Web of Conferences, 2014 Building Information Modeling (BIM) has been considered as a solution in construction industry to numerous problems such as delays, increased lead in times and increased costs.
Omar Mohd Faizal +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
, 2011 Componente Curricular::Educação Superior::Ciências Exatas e da Terra::MatemáticaComponente Curricular::Ensino Médio::MatemáticaThe Poly Pro is a better version of Poly.
Pedagoguery Software Inc.
core
Software maintenance: generating front ends for cross referencer tools [PDF]
, 1989 This thesis surveys the activities performed in software maintenance and identifies some of the software tools which can be utilised by the maintenance programmer.
Turver, Richard John
core
Application of JKSimBlast software in drifting operations [PDF]
Podzemni Radovi, 2019 This paper presents a review of the advantages of application of JKSimBlast 2DFace software in design phase of underground premises. The aim of this research was to show possibilities of the software and possibility of its application in design of ...
Crnogorac Luka +4 more
doaj
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
, 2009 The Poly Pro is a better version of Poly. Software for exploration and construction of polyhedrasThe user must know how to identify polyhedras and have knowledge of geometry to build themComponente Curricular::Ensino Médio::MatemáticaComponente ...
Pedagoguery Software Inc.
core
eLearning Modules – Increasing Knowldege Of Collaboration Tools For Construction Management [PDF]
, 2006 Web based collaboration software, such as Optus inCITE and IFC compliant construction management software, offers the opportunity for construction project teams to design and communicate more cost effectively, to plan construction more efficiently, and ...
Wall, John +3 more
core
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source