Results 161 to 170 of about 5,981,001 (327)

Analysis of the construction of the concepts of proportionality using the software Geoplano Virtual

, 2013
Leandra Anversa Fioreze, Igor Yepes, Marcus Vinícius de Azevedo Basso, Silvia Maria de Aguiar Isaia   +3 more
openalex   +1 more source

A Mathematical Framework of Human Thought Process: Rectifying Software Construction Inefficiency and Identifying Characteristic Efficiencies of Networked Systems Via Problem-solution Cycle

, 2015
Jonathan Sarbah-Yalley, Jonathan Sarbah-Yalley   +1 more
openalex   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Impact of personal protective equipment in preventing occupational injuries: a systematic review and meta-analysis. [PDF]

Front Public Health
Santos W, Lorente A, Rojas C, Mariscal G, Lorente R.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Prediction method for rock shear strength parameters based on data-driven and interpretability analysis. [PDF]

Sci Rep
Jin ZJ, Wang C, Qi S, Liu Y, Yu H, He ZW.   +5 more
europepmc   +1 more source

Critical success aspects in project management: similarities and differences between the construction and software industry

, 2014
Jo�ão Varaj�ão, Caroline Domínguez, Pedro Ribeiro, Anabela Paiva   +3 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Correction: Construction of a prognostic model for colorectal cancer liver metastasis based on single-cell transcriptomics and regulation of the MIF pathway. [PDF]

Front Oncol
Cao J, He Z, Gao H, Yu Y, Yang S, Wang X, Niu J, Peng C.   +7 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source