Results 31 to 40 of about 7,286,866 (372)

Large-scale Complex IT Systems [PDF]

open access: yes, 2011
This paper explores the issues around the construction of large-scale complex systems which are built as 'systems of systems' and suggests that there are fundamental reasons, derived from the inherent complexity in these systems, why our current software
Antoniou G.   +11 more
core   +2 more sources

In silico drug repositioning based on the integration of chemical, genomic and pharmacological spaces

open access: yesBMC Bioinformatics, 2021
Background Drug repositioning refers to the identification of new indications for existing drugs. Drug-based inference methods for drug repositioning apply some unique features of drugs for new indication prediction. Complementary information is provided
Hailin Chen, Zuping Zhang, Jingpu Zhang
doaj   +1 more source

Implications of heterogeneous fracture distribution on reservoir quality; an analogue from the Torridon Group sandstone, Moine Thrust Belt, NW Scotland [PDF]

open access: yes, 2017
This research was funded by a NERC CASE studentship (NERC code NE/I018166/1) in partnership with Midland Valley. Midland Valley's Move software was used for cross section construction and strain modelling.
Bond, Clare E.   +3 more
core   +1 more source

An experimental verification system for electric vehicle and grid interactive charging safety

open access: yesFrontiers in Energy Research
The development of electric vehicles (EVs) reduces dependence on fossil fuels, promotes energy conservation and emissions reduction, and facilitates the transition to clean energy sources in the power grid.
Jun Han   +4 more
doaj   +1 more source

Integrating Multiple Interaction Networks for Gene Function Inference

open access: yesMolecules, 2018
In the past few decades, the number and variety of genomic and proteomic data available have increased dramatically. Molecular or functional interaction networks are usually constructed according to high-throughput data and the topological structure of ...
Jingpu Zhang, Lei Deng
doaj   +1 more source

In silico drug repositioning based on integrated drug targets and canonical correlation analysis

open access: yesBMC Medical Genomics, 2022
Background Besides binding to proteins, the most recent advances in pharmacogenomics indicate drugs can regulate the expression of non-coding RNAs (ncRNAs).
Hailin Chen, Zuping Zhang, Jingpu Zhang
doaj   +1 more source

Lightweight Call-Graph Construction for Multilingual Software Analysis

open access: yes, 2018
Analysis of multilingual codebases is a topic of increasing importance. In prior work, we have proposed the MLSA (MultiLingual Software Analysis) architecture, an approach to the lightweight analysis of multilingual codebases, and have shown how it can ...
Baird, David   +2 more
core   +1 more source

Formalising responsibility modelling for automatic analysis [PDF]

open access: yes, 2015
Modelling the structure of social-technical systems as a basis for informing software system design is a difficult compromise. Formal methods struggle to capture the scale and complexity of the heterogeneous organisations that use technical systems ...
Simpson, Robert, Storer, Tim
core   +1 more source

A Localized Collocation Solver Based on T-Complete Functions for Anti-Plane Transverse Elastic Wave Propagation Analysis in 2D Phononic Crystals

open access: yesMathematical and Computational Applications, 2020
In this paper, we introduce a novel localized collocation solver for two-dimensional (2D) phononic crystal analysis. In the proposed collocation solver, the displacement at each node is expressed as a linear combination of T-complete functions in each ...
Zhuo-Jia Fu   +3 more
doaj   +1 more source

Implementing atomic actions in Ada 95 [PDF]

open access: yes, 1997
Atomic actions are an important dynamic structuring technique that aid the construction of fault-tolerant concurrent systems. Although they were developed some years ago, none of the well-known commercially-available programming languages directly ...
Burns, A, Wellings, A
core   +1 more source

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