Results 31 to 40 of about 2,152,161 (366)

In silico drug repositioning based on integrated drug targets and canonical correlation analysis

open access: yesBMC Medical Genomics, 2022
Background Besides binding to proteins, the most recent advances in pharmacogenomics indicate drugs can regulate the expression of non-coding RNAs (ncRNAs).
Hailin Chen, Zuping Zhang, Jingpu Zhang
doaj   +1 more source

In silico drug repositioning based on the integration of chemical, genomic and pharmacological spaces

open access: yesBMC Bioinformatics, 2021
Background Drug repositioning refers to the identification of new indications for existing drugs. Drug-based inference methods for drug repositioning apply some unique features of drugs for new indication prediction. Complementary information is provided
Hailin Chen, Zuping Zhang, Jingpu Zhang
doaj   +1 more source

An experimental verification system for electric vehicle and grid interactive charging safety

open access: yesFrontiers in Energy Research
The development of electric vehicles (EVs) reduces dependence on fossil fuels, promotes energy conservation and emissions reduction, and facilitates the transition to clean energy sources in the power grid.
Jun Han   +4 more
doaj   +1 more source

Integrating Multiple Interaction Networks for Gene Function Inference

open access: yesMolecules, 2018
In the past few decades, the number and variety of genomic and proteomic data available have increased dramatically. Molecular or functional interaction networks are usually constructed according to high-throughput data and the topological structure of ...
Jingpu Zhang, Lei Deng
doaj   +1 more source

A Localized Collocation Solver Based on T-Complete Functions for Anti-Plane Transverse Elastic Wave Propagation Analysis in 2D Phononic Crystals

open access: yesMathematical and Computational Applications, 2020
In this paper, we introduce a novel localized collocation solver for two-dimensional (2D) phononic crystal analysis. In the proposed collocation solver, the displacement at each node is expressed as a linear combination of T-complete functions in each ...
Zhuo-Jia Fu   +3 more
doaj   +1 more source

Design and Validation of a Mobile Application for Construction and Demolition Waste Traceability

open access: yesBuildings, 2023
Many studies have developed technologies intended to automate the process toward improving sustainability and achieving a circular economy in the construction industry.
Paola Villoria Sáez   +4 more
doaj   +1 more source

Lightweight Call-Graph Construction for Multilingual Software Analysis

open access: yes, 2018
Analysis of multilingual codebases is a topic of increasing importance. In prior work, we have proposed the MLSA (MultiLingual Software Analysis) architecture, an approach to the lightweight analysis of multilingual codebases, and have shown how it can ...
Baird, David   +2 more
core   +1 more source

Efficient and Robust Syslog Parsing for Network Devices in Datacenter Networks

open access: yesIEEE Access, 2020
Syslog parsing is of vital importance for the detection, diagnosis and prediction of network device failures in a datacenter. A common approach to syslog parsing is to extract templates from historical syslogs, after which syslogs are matched to these ...
Shenglin Zhang   +10 more
doaj   +1 more source

Scientists in the MIST: Simplifying Interface Design for End Users [PDF]

open access: yes, 2006
We are building a Malleable Interactive Software Toolkit (MIST), a tool set and infrastructure to simplify the design and construction of dynamically-reconfigurable (malleable) interactive software.
Bhatia, Saurabh   +4 more
core   +1 more source

Detailed kinship estimation for detecting bias among breeding families in a reintroduced population of the endangered bagrid catfish Tachysurus ichikawai

open access: yesPopulation Ecology, EarlyView.
In the process of captive breeding and reintroduction of endangered animal species, it is crucial to minimize familial bias in reproductive success during the reintroduction phase to preserve genetic diversity. In this study, we attempted to identify the familial lineage of individuals of the endangered bagrid fish Tachysurus ichikawai born at the ...
Hinano Mizuno   +5 more
wiley   +1 more source

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