Results 51 to 60 of about 2,152,161 (366)
FEBS Letters, EarlyView.We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti +2 more
wiley +1 more source
Happy software developers solve problems better: psychological measurements in empirical software engineering [PDF]
PeerJ, vol. 2, pp. e289, 2014, 2015 For more than 30 years, it has been claimed that a way to improve software developers' productivity and software quality is to focus on people and to provide incentives to make developers satisfied and happy. This claim has rarely been verified in software engineering research, which faces an additional challenge in comparison to more traditional ...
arxiv +1 more source
Requirements for software engineering languages [PDF]
, 1985 This paper analyzes the concepts of software construction embodied in the Draco system. The analysis relates specific mechanisms in Draco to particular software engineering (SE) principles and suggests future research needed to extend the approach.
Freeman, Peter, Staa, Arndt von
core +1 more source
Benchmarking of project planning and success in selected industries [PDF]
, 2015 Purpose - To identify the industry in which projects are best planned and executed and use it as a benchmark for improving project planning in other industries.
Globerson, Shlomo, Zwikael, Ofer
core +1 more source
FEBS Letters, EarlyView.The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang +9 more
wiley +1 more source
FEBS Letters, EarlyView.The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley +2 more
wiley +1 more source
Towards a Structural Equation Model of Open Source Blockchain Software Health [PDF]
arXiv, 2023 The widespread use of GitHub among software developers as a communal platform for coordinating software development has led to an abundant supply of publicly accessible data. Ever since the inception of Bitcoin, blockchain teams have incorporated the concept of open source code as a fundamental principle, thus making the majority of blockchain-based ...
arxiv
Software engineering and middleware: a roadmap (Invited talk) [PDF]
, 2000 The construction of a large class of distributed systems can be simplified by leveraging middleware, which is layered between network operating systems and application components.
Emmerich, W.
core
Implications of heterogeneous fracture distribution on reservoir quality; an analogue from the Torridon Group sandstone, Moine Thrust Belt, NW Scotland [PDF]
, 2017 This research was funded by a NERC CASE studentship (NERC code NE/I018166/1) in partnership with Midland Valley. Midland Valley's Move software was used for cross section construction and strain modelling.
Bond, Clare E. +3 more
core +1 more source
FEBS Letters, EarlyView.In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri +8 more
wiley +1 more source