Results 51 to 60 of about 5,981,001 (327)

Research on community characteristics of vegetation restoration in hilly power engineering based on multi temporal remote sensing technology

Open Geosciences
In order to accurately identify and evaluate the interference caused to vegetation environment during the construction process of current power transmission and transformation projects in hilly areas, especially in response to the obvious shortcomings of
Chen Bin, Lei Dong, Huang Liangjun, Liu Qingdong, Zhao Xuan, Shi Yuanping   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Point cloud filtering algorithm of water and soil loss in the disturbed area of the power transmission and transformation project based on CSF

Geocarto International
The accuracy of laser point cloud data is crucial for soil erosion control in engineering disturbance areas. This study applies the Fabric Simulated Filter (CSF) to filter point clouds collected by a mobile stereo panoramic vision sensor system from ...
Bin Chen, Jia Feng, Zhengdong Zhou, Chengcheng Xu, Licai Yan, Lijuan Xu   +5 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Object-oriented software construction at ALS [PDF]

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1994
Abstract C++ class libraries have been developed and used for accelerator modeling and machine control at the Advanced Light Source. A class library for accelerator modeling is portable and supports multiple model instances dynamically at run time. A class library for machine control covers fields from virtual devices to simulation studies.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Concurrent Deterministic Execution Semantics for IEC 61499-Based OT–IT Convergence Industrial Edge Applications

IEEE Open Journal of the Industrial Electronics Society
Industrial edge computing provides new possibilities for traditional industrial automation systems. With massive computing, storage, and communication resources equipped with devices on the shop floor, a typical edge device can simultaneously handle ...
Wenbin Dai, Shang Gao, Kaiyun Qin, Chuanyang Yu, Dongdong Zhang, Likuan Zhang, Hui Zhang   +6 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

FieldManager® – Construction Management Software

, 2010
The FieldManager® software is a construction management system jointly owned by the Michigan Department of Transportation (MDOT) and Info Tech, Inc. Designed for any size organization that manages construction projects, FieldManager software wraps up contract documentation and reporting, contract modifications, and pay estimates into one neat package ...
openaire   +5 more sources