Results 51 to 60 of about 5,734,084 (343)

Research on community characteristics of vegetation restoration in hilly power engineering based on multi temporal remote sensing technology

open access: yesOpen Geosciences
In order to accurately identify and evaluate the interference caused to vegetation environment during the construction process of current power transmission and transformation projects in hilly areas, especially in response to the obvious shortcomings of
Chen Bin   +5 more
doaj   +1 more source

FieldManager® – Construction Management Software

open access: yes, 2010
The FieldManager® software is a construction management system jointly owned by the Michigan Department of Transportation (MDOT) and Info Tech, Inc. Designed for any size organization that manages construction projects, FieldManager software wraps up contract documentation and reporting, contract modifications, and pay estimates into one neat package ...
openaire   +4 more sources

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Object-oriented software construction at ALS [PDF]

open access: yesNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1994
Abstract C++ class libraries have been developed and used for accelerator modeling and machine control at the Advanced Light Source. A class library for accelerator modeling is portable and supports multiple model instances dynamically at run time. A class library for machine control covers fields from virtual devices to simulation studies.
openaire   +3 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Research on the Informatization Construction and Development Mode of Internal Control in Colleges and Universities Based on Game Model

open access: yesDiscrete Dynamics in Nature and Society, 2022
With the advancement of information technology, the informatization construction of internal control has evolved into crucial fundamental support for the construction of internal control in colleges and universities.
Yuzhen Cheng
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Construction of Membership Function for Software Metrics

open access: yesProcedia Computer Science, 2015
AbstractA software developer has to deal with a lot of challenging requirements such as cost prediction, defect prediction, reliability prediction, testing effort prediction, safety prediction, and many more while developing quality software. However, it has been found that the most of the software development activity is performed by human beings ...
Dilip Kumar Yadav   +1 more
openaire   +2 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

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