Results 81 to 90 of about 2,092,569 (323)

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Software Toolchain for Large-Scale RE-NFA Construction on FPGA

open access: yesInternational Journal of Reconfigurable Computing, 2009
We present a software toolchain for constructing large-scale regular expression matching (REM) on FPGA. The software automates the conversion of regular expressions into compact and high-performance nondeterministic finite automata (RE-NFA).
Yi-Hua E. Yang, Viktor K. Prasanna
doaj   +1 more source

A study into the feasibility of generic programming for the construction of complex software [PDF]

open access: yes, 2003
A high degree of abstraction and capacity for reuse can be obtained in software design through the use of Generic Programming (GP) concepts. Despite widespread use of GP in computing, some areas such as the construction of generic component libraries as ...
Caballé Llobet, Santiago   +1 more
core  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Public-participant quick cable force investigation method using smartphone for bridges in disaster area

open access: yesAdvances in Mechanical Engineering, 2016
Numerous infrastructures, especially the bridge, require some safe inspection and assessment at the soonest when hit by a disaster like catastrophic earthquake.
Xuefeng Zhao   +6 more
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Software Design for Affordable Quality Construction

open access: yes, 2017
IT is an integral part of CRM to meet customers need. In this work, I designed UML use cases and scenarios for the Affordable Quality Construction.
openaire   +2 more sources

SAGA: A project to automate the management of software production systems [PDF]

open access: yes
The project to automate the management of software production systems is described. The SAGA system is a software environment that is designed to support most of the software development activities that occur in a software lifecycle.
Badger, W.   +9 more
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

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