Results 81 to 90 of about 2,152,161 (366)

The Synonym management process in SAREL [PDF]

open access: yes, 2002
The specification phase is one of the most important and least supported parts of the software development process. The SAREL system has been conceived as a knowledge-based tool to improve the specification phase.
Castell Ariño, Núria   +1 more
core   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Software Must Move! A Description of the Software Assembly Line [PDF]

open access: yesProceedings of the IEEE SOFTFAIR -- A CONFERENCE ON SOFTWARE DEVELOPMENT TOOLS, TECHNIQUES, and ALTERNATIVES, 1983, 2010
This paper describes a set of tools for automating and controlling the development and maintenance of software systems. The mental model is a software assembly line. Program design and construction take place at individual programmer workstations. Integration of individual software components takes place at subsequent stations on the assembly line ...
arxiv  

Secure Software Licensing: Models, Constructions, and Proofs [PDF]

open access: yes2016 IEEE 29th Computer Security Foundations Symposium (CSF), 2016
The problem of secure software licensing is to enforce meaningful restrictions on how software is run on machines outside the control of the software author/vendor. The problem has been addressed through a variety of approaches from software obfuscation to hardware-based solutions, but existent solutions offer only heuristic guarantees which are often ...
Costea, Sergiu, Warinschi, Bogdan
openaire   +4 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Track My Hoist [PDF]

open access: yes, 2017
Construction sites all over the world rely on hoist lifts for transporting material and workers at the job site. Despite being such an integral part of construction projects, there is currently no tool to track the use of this critical and highly ...
Harrison, Brett   +2 more
core   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

A Framework for Evaluating Model-Driven Self-adaptive Software Systems [PDF]

open access: yesarXiv, 2019
In the last few years, Model Driven Development (MDD), Component-based Software Development (CBSD), and context-oriented software have become interesting alternatives for the design and construction of self-adaptive software systems. In general, the ultimate goal of these technologies is to be able to reduce development costs and effort, while ...
arxiv  

Achieving higher capability maturity in construction process improvement [PDF]

open access: yes
Process improvement has been identified as one of the potential mechanisms to achieve the desired performance improvements within the UK construction industry.
Amaratunga, Dilanthi   +2 more
core  

Panphasia: a user guide [PDF]

open access: yes, 2013
We make a very large realisation of a Gaussian white noise field, called PANPHASIA, public by releasing software that computes this field. Panphasia is designed specifically for setting up Gaussian initial conditions for cosmological simulations and ...
Booth, Stephen, Jenkins, Adrian
core  

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