Results 91 to 100 of about 5,927,341 (295)

Flexible open network operating system architecture for implementing higher scalability using disaggregated software‐defined optical networking

IET Networks
The enhanced capacity of optical networks is a significant advantage within the global telecommunications industry. Optical networks provides transmission of information over large distances with reduced latency. However, the growing intricacy of network
Kenneth Nsafoa‐Yeboah, Eric Tutu Tchao, Benjamin Kommey, Andrew Selasi Agbemenu, Griffith Selorm Klogo, Nana Kwadwo Akrasi‐Mensah   +5 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Test derivation for the software defined networking platforms: novel fault models and test completeness

, 2018
Software Defined Networking (SDN) platforms ...
Lopez Coronado, Jorge Eleazar, Kossachev, Alexandre, Yevtushenko, Nina V., Zeghlache, Djamal, Yevtushenko, Nina, Burdonov, Igor, López, Jorge, Kushik, Natalia G., Kushik, Natalia, Igor Burdonov, Alexandre Kossachev, Jorge Lopez, Natalia Kushik, Djamal Zeghlache, Nina Yevtushenko   +14 more
core   +2 more sources

SOFTWARE DEFINED NETWORKING CONTEXT DISSOCIATION [PDF]

, 2018
Context dissociation techniques are described herein for Software Defined Networking (SDN) applications. This prevents a poor user experience wherein the user is forced to look at a spinner until the operation is ...
Gopalakrishnan, Anand Pulicat, Sheeran, Kevin, David, Jerry, Mishra, Ramesh   +3 more
core  

Assessing the risk of violating SLA dependability requirements in software-defined networks [PDF]

, 2017
Dependability of computer and communication networks is an important aspect of the customer-provider relationship in the telecommunication industry. Considering the increasing interest in Software-Defined Networking (SDN) technologies, as well as unclear
Bjarne E. Helvik, Gianfranco Nencioni, Gonzalez, Andres Javier, Helvik, Bjarne Emil, Kamisiński, Andrzej, Andres J. Gonzalez, Nencioni, Gianfranco, Andrzej Kamisinski   +7 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Traffic engineering in software-defined networking: Measurement and management

IEEE Access, 2016
As the next generation network architecture, software-defined networking (SDN) has exciting application prospects. Its core idea is to separate the forwarding layer and control layer of network system, where network operators can program packet ...
Zhaogang Shu, Jiafu Wan, Jiaxiang Lin, Shiyong Wang, Di Li, Seungmin Rho, Changcai Yang   +6 more
doaj   +1 more source

Towards Test-Driven Software Defined Networking

, 2014
To configure, troubleshoot and operate their networks, operators often have no alternatives than relying on error-prone manual procedures. The emerging Software Defined Networking paradigm opens new possibilities for more structured networking ...
Lebrun, David, Vissicchio, Stefano, IEEE/IFIP NOMS, Bonaventure, Olivier   +3 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source